| Livin在人喉癌细胞中的表达及白毛藤多糖的干预作用 |
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| 引用本文： | 张杰,杨旭东,李孟全,宋高臣,申梅淑,宗灿华,刘洪凤.Livin在人喉癌细胞中的表达及白毛藤多糖的干预作用[J].中国食物与营养,2013(6):65-67. |
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| 作者姓名： | 张杰 杨旭东 李孟全 宋高臣 申梅淑 宗灿华 刘洪凤 |
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| 作者单位： | 牡丹江医学院 |
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| 基金项目： | 黑龙江省中医药管理局中医药科研项目“白毛藤诱导肿瘤细胞凋亡有效成分筛选及其机制研究”(项目编号:ZHY10-W71) |
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| 摘 要： | 研究白毛藤多糖对人喉癌细胞生长的抑制作用以及Livin表达的影响。将白毛藤多糖以不同浓度加入到人喉癌细胞，用M1Tr比色法检测细胞增殖抑制率；荧光定量PCR检测LivinmRNA的表达。结果表明，白毛藤多糖可诱导Livin基因的表达，Livin可能参与白毛藤多糖抑制人喉癌细胞的增殖。
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| 关 键 词： | 白毛藤多糖 人喉癌细胞 Livin基因 |
Expression of Livin in Human Laryngeal Carcinoma Cells and the Intervention Effect of Solamum lyratum Polysaccharides |
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| ZHANG Jie,YANG Xu-dong,LI Meng-quan,SONG Gao-chen SHEN Mei-shu,ZONG Can-hua,LIU Hong-feng.Expression of Livin in Human Laryngeal Carcinoma Cells and the Intervention Effect of Solamum lyratum Polysaccharides[J].Food and Nutrition in China,2013(6):65-67. |
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| Authors: | ZHANG Jie YANG Xu-dong LI Meng-quan SONG Gao-chen SHEN Mei-shu ZONG Can-hua LIU Hong-feng |
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| Affiliation: | (Mudanjiang Medical College,Mudanjiang 157011,China) |
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| Abstract: | To investigate the inhibition of Solamum lyratum polysaccharides on human laryngeal carcinoma cells invito. Human larynge- al carcinoma cells were treated with various concentration of Solamum lyratum polysaccharides. The proliferation inhibition ratio was evaluated by MT＇F. The expression of Livin gene was detected by RT-PCR. Results showed that Solamum lyratum polysaccharides could inhibit the hu-man laryngeal carcinoma cells proliferation by regulating the expression of Livin gene. |
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| Keywords: | Solamum lyratum polysaccharides human laryngeal carcinoma cell Livin |
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