Action of γ-aminobutyric acid and glycine on red nucleus neurones

Summary GABA and glycine were applied iontophoretically in the red nucleus. Their effects were tested upon focal potentials in extracellular records, and upon the cell membrane (polarization, conductance, amplitude of spike and synaptic potentials) of rubrospinal neurons in intracellular records. Both GABA and glycine reduced the amplitude of focal potentials, hyperpolarized the membrane and increased its conductance. Quantitatively GABA actions were clearly more pronounced than glycine actions, based on the comparison of iontophoretic currents.Supported by: Deutsche Forschungsgemeinschaft (Grant Br 242/7).