乌鸡黑色素在果蝇体内排铅解毒的研究

以黄体果蝇为实验动物,研究2种乌鸡黑色素添加水平(0.02mg/mL和0.2mg/mL)对果蝇在高铅(2mg/mL)条件下平均寿命和体内铅含量的影响。结果表明:乌鸡黑色素能显著提高果蝇的平均寿命(P<0.05),延寿率达70.2%和54.9%。与阳性对照(1262.0±363.1)μg/g相比,添加0.2mg/mL黑色素能显著(P<0.05)降低果蝇体内铅含量(949.7±38.4)μg/g达32.9%。因此,乌鸡黑色素对果蝇具有一定排铅解毒作用。

Effect of Melanin Derived from White Silky Fowl on Accumulation and Toxicity of Lead in Drosophila melanogaster

Yellow(y) strain of Drosophila melanogaster was used to evaluate protective power of melanin from white silky fowl added in the cultural medium in the concentration of 0.02 and 0.2mg/mL against toxicity and accumulation of lead.The results were as follows: melanin can efficiently(P < 0.05) improve mean longevity of yellow strain by 70.2% and 54.9% respectively under high concentration of lead(2 mg/mL).Furthermore,melanin(0.2 mg/mL) can significantly decrease(P < 0.05) accumulation(949.7±38.4) μg/g of lead in yellow strain by 32.9%,compared with the positive group(1262.0±363.1) μg/g.Therefore,melanin from white silky fowl might play a positive role in extending longevity and reducing accumulation of lead in flies reared under high concentration of lead.