| 糖皮质激素致乙型肝炎病毒再激活死亡1例报道 |
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| 引用本文： | 廖献花,马博,林菁华,徐雅,刘思纯.糖皮质激素致乙型肝炎病毒再激活死亡1例报道[J].胃肠病学和肝病学杂志,2010,19(3). |
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| 作者姓名： | 廖献花 马博 林菁华 徐雅 刘思纯 |
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| 作者单位： | 中山大学附属第一医院黄埔院区消化科,广东,广州,510700 |
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| 摘 要： | 我国是乙型肝炎病毒(HBV)感染高流行区,HBV感染者在接受免疫抑制剂或细胞毒性药物治疗期间或之后,可能出现不同程度的HBV再激活,死亡率较高。预防性应用拉米夫定等抗乙肝病毒药物可有效降低HBV再激活发生率和死亡率。本文报道1例糖皮质激素治疗致HBV再激活死亡的病例,并结合文献复习,探讨并提高对HBV再激活的发生率、危险因素、诊断及治疗等的认识。
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| 关 键 词： | 乙型病毒性肝炎 再激活 糖皮质激素 免疫抑制剂 细胞毒性药物 |
Death due to reactivation of hepatitis B virus caused by glucocorticoid:one case report |
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| LIAO Xianhua,MA Bo,LIN Jinghua,XU Ya,LIU Sichun.Death due to reactivation of hepatitis B virus caused by glucocorticoid:one case report[J].Chinese Journal of Gastroenterology and Hepatology,2010,19(3). |
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| Authors: | LIAO Xianhua MA Bo LIN Jinghua XU Ya LIU Sichun |
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| Affiliation: | LIAO Xianhua,MA Bo,LIN Jinghua,XU Ya,LIU SichunDepartment of Gastroenterology,Huangpu Branch,the Affiliated First Hospital,Sun Yat-sen University,Guangzhou 510700,China |
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| Abstract: | Hepatitis B virus(HBV) infection is an important medical and public health concern.Patients with hepatitis B are at risk of viral reactivation when undergoing cytotoxic or immunosuppressive chemotherapy for malignancies.The condition ranges from asymptomatic self-limiting anicteric hepatitis to severe, potentially fatal progressive decompensated hepatitis.Prophylactic therapy with nucleoside analogues has been shown to significantly decrease the incidence and overall morbidity of HBV reactivation.Here we re... |
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| Keywords: | Hepatitis B virus Reactivation Glucocorticoid Immunosuppressor Cytotoxic drug |
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