| 修复性牙本质形成的大鼠模型 |
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| 引用本文： | 陈智,樊明文,边专,彭彬,熊卫星.修复性牙本质形成的大鼠模型[J].牙体牙髓牙周病学杂志,2000,10(3):139-142. |
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| 作者姓名： | 陈智 樊明文 边专 彭彬 熊卫星 |
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| 作者单位： | 湖北医科大学口腔医学院,湖北,武汉,430079 |
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| 基金项目： | 湖北省自然科学基金!( 98J0 86) |
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| 摘 要： | 目的：建立修复性牙本质形成的动物实验模型，观察修复性牙本质形成的组织开矿学特征。方法：在Ｗｉｓｔａｒ大鼠第一磨牙近中面制备窝洞，分别观察３、１５、３０ｄ，标本切片，ＨＥ染色，显微镜下观察。结果：术后３ｄ未见修复性牙本质形成。１５ｄ后可见修复性牙本工可见骨样牙本质。窝洞下原代成牙本质细胞由新分化的成牙本质细胞样细胞取代。３０ｄ后，修复性牙本质明显增加。新分化的成牙本质细胞样细胞发生极化。结论：大鼠模
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| 关 键 词： | 修复性牙本质形成 成牙本质细胞 大鼠 |
| 修稿时间： | 1999-10-20 |
Reparative dentinogenesis in rats model |
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| CHEN Zhi,FAN Ming-wen,BIAN Zhuan,et al School of Stomatology,Hubei Medical University,Wuhan $$$$.Reparative dentinogenesis in rats model[J].Chinese Journal of Conservative Dentistry,2000,10(3):139-142. |
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| Authors: | CHEN Zhi FAN Ming-wen BIAN Zhuan School of Stomatology Hubei Medical University Wuhan $$$$ |
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| Affiliation: | CHEN Zhi,FAN Ming-wen,BIAN Zhuan,et al School of Stomatology,Hubei Medical University,Wuhan 430079$$$$ |
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| Abstract: | AIM: To establish the animal model of reparative dentinogenesis and investigate the histo-morphological feature of reparative dentinogenesis. METHODS: The cavity was prepared on the mesial surface of the first molars of Wistar rats. The rats were sacrificed at 3, 15, and 30 days of post-operation. The samples were stained by HE, observed under microscope. RESULTS: No reparative dentin was formed after 3 days of post-operation. The new-formed reparative dentin and osteodentin were observed after 15 days. The primary odontoblasts were disappeared and replaced by odontoblast-like cell. Reparative dentin increased with an irregular tubular structure after 30 days. The odontoblast-like cells were in polarization. CONCLUSION: This study demonstrated the process of reparative dentinogenesis. Rat is a good animal model for the study of reparative dentinogenesis. |
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| Keywords: | reparative dentin dentinogenesis odontoblast rat |
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