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均匀设计法优选贯叶连翘总黄酮的提取工艺
引用本文:王刚. 均匀设计法优选贯叶连翘总黄酮的提取工艺[J]. 辽宁中医杂志, 2010, 0(2): 320-321
作者姓名:王刚
作者单位:遵义医学院药物化学教研室;
基金项目:贵州省科技厅科技基金课题(黔科合J字[2009]2152号)
摘    要:目的:优选贯叶连翘总黄酮提取工艺。方法:以总黄酮含量为指标,采用均匀设计法筛选最佳提取工艺。结果:最佳提取工艺为10倍量90%乙醇回流2次,60min/次,贯叶连翘中总黄酮的含量为9.12%,与理论推测相符。结论:优化提取工艺简单、稳定、可行。

关 键 词:贯叶连翘  总黄酮  均匀设计  提取工艺

Extraction of Total Flavonoids From Hypericum Perforatum Based on Uniform Design Method
WANG Gang. Extraction of Total Flavonoids From Hypericum Perforatum Based on Uniform Design Method[J]. Liaoning Journal of Traditional Chinese Medicine, 2010, 0(2): 320-321
Authors:WANG Gang
Affiliation:Department of Medicinal Chemistry/a>;Zunyi Medical College/a>;Zunyi 563003/a>;Guizhou/a>;China
Abstract:Objective:To optimize the extraction technology of the total flavonoids from Hypericum perforatum.Methods:Selecting the contents of total flavonoids from the extractsolution as the target,the conditions of extraction were optimized by the uniform design method.Results:The optimum extraction technology was as follows:solid-liquid ratio 1∶10,90% ethanol,refluxing and extracting for 60 min,2 times.The total flavonoids in Hypericum perforatum was 9.12%.Conclusion:This optimized process is simple,stable and efficient.
Keywords:Hypericum perforatum  total flavonoids  uniform design method  extraction technique  
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