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HCV核酸检测用于临床诊断的研究进展
引用本文:徐冰,赫晓霞,任雅楠,王俊,邢文革. HCV核酸检测用于临床诊断的研究进展[J]. 中华流行病学杂志, 2021, 42(1): 153-159
作者姓名:徐冰  赫晓霞  任雅楠  王俊  邢文革
作者单位:中国疾病预防控制中心性病艾滋病预防控制中心参比实验室, 北京 102206;北京市理化分析测试中心 北京市食品安全分析测试工程技术研究中心 北京市基因测序与功能分析工程技术研究中心 100089
摘    要:HCV感染呈全球流行,发病隐匿。实验室检测是临床诊断的主要依据,其检测方法主要为抗体检测和核酸检测。为实现对HCV感染的早发现、早诊断,选择最佳检测方法和诊断策略尤为重要。本文从HCV核酸检测方法,试剂的性能评价以及目前的HCV检测策略进行综述。

关 键 词:HCV  核酸检测  检测策略
收稿时间:2020-03-17

Advances in studies of HCV nucleic acid testing for clinical diagnosis
Xu Bing,He Xiaoxi,Ren Yanan,Wang Jun,Xing Wenge. Advances in studies of HCV nucleic acid testing for clinical diagnosis[J]. Chinese Journal of Epidemiology, 2021, 42(1): 153-159
Authors:Xu Bing  He Xiaoxi  Ren Yanan  Wang Jun  Xing Wenge
Affiliation:National HIV/AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention. Beijing 102206, China;Beijing Engineering Technology Research Centre of Gene Sequencing and Gene Function Analysis, Beijing Engineering Research Center of Food Safety Analysis, Beijing Center for Physical & Chemical Analysis, Beijing 100089, China
Abstract:HCV infection is of global concern with the characteristic of insidious onset. Laboratory testing stands indispensably for clinical diagnosis with antibody assay and nucleic acid testing the main methods being adopted. For early detection and diagnosis of HCV infection, it is important to choose the best detection method and diagnostic strategy. This paper reviews the HCV nucleic acid testing methods, as well as performance evaluation of reagents and current strategies.
Keywords:HCV  Nucleic Acid Testing  Testing Strategy
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