| 替硝唑体内抗厌氧菌感染作用的研究 |
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| 引用本文： | 孙延波,李淑华.替硝唑体内抗厌氧菌感染作用的研究[J].中国微生态学杂志,1996,8(2):14-16. |
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| 作者姓名： | 孙延波 李淑华 |
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| 作者单位： | 白求恩医科大学微生物学教研室，长春医学高等专科学校 |
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| 摘 要： | 本项研究观察了替硝唑对类杆菌，经腹腔感染小鼠的体内保护作用。结果显示替硝唑对脆弱类杆菌和产黑色素类杆菌感染的小鼠，均具有良好的保护作用，两株菌感染的半数有效剂量（ＥＤ５０）分别为１１．１５ｍｇ／ｋｇ和１３．０４ｍｇ／ｋｇ。与甲硝唑相比，两者无显著性差异。
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| 关 键 词： | 替硝唑，厌氧菌，半数有效剂量 |
IN VIVO EFFECT OF TINIDAZOLE AGAINST ANAEROBIC BACTERIA |
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| Sun Yanbo,et al..IN VIVO EFFECT OF TINIDAZOLE AGAINST ANAEROBIC BACTERIA[J].Chinese Journal of Microecology,1996,8(2):14-16. |
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| Authors: | Sun Yanbo |
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| Abstract: | In vivo effect of Tinidazole against Bacteroids was studied through intra-abdominal infection.The results showed that Tinidazole was very effective to the infections of B.fragilis and B.melaninogenicus in mice.The ED50 of Tinidazole against infections with B.fragilis and B.melaninogenicus was 11.15mg/kg and 13.04mg/kg,respectively.In comparision with Metronidazole,there is no difference between them. |
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| Keywords: | Tinidazole Anaerobic bacteria 50% Effective dose(ED50) |
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