BODIPY基荧光探针的合成、表征及对铜离子的检测——推荐一个大学综合化学实验

介绍了一个大学综合化学实验——BODIPY基荧光探针的合成、表征及对铜离子的检测。该实验是一个科研转化的大学生综合化学实验,内容包括3,5-二氯BODIY的合成、BODIPY基荧光探针分子的合成,以及利用紫外-可见分光光度计和荧光光谱仪检测目标分子对金属离子的响应性。通过本实验,使学生了解BODIPY基荧光传感器这一科研前沿领域,激发学生对科学研究的兴趣,培养学生的科研探究能力。本实验综合了有机化学、仪器分析和应用波谱学知识点的学习,培养学生的实验操作技能,提升学生的综合及创新能力,建议纳入高年级综合化学实验课程。

Synthesis and Characterization of a BODlPY Fluorescent Probe and lts Application in Detection of Cu2+lons:A Comprehensive Chemical Experiment for College Students

A new comprehensive chemical experiment for college students is introduced, including the synthesis and characterization of a fluorescent probe based on BODIPY, as well as its application in detection of Cu²⁺ ions. This experiment is from the achievements of scientific research. It includes the synthesis of 3, 5-dichloro-8-(4-tolyl)BODIPY, the synthesis of a fluorescent probe based on BODIPY, and the detection of metal ions by UV-Vis spectrometer and Fluorescence spectrometer. Students' interest in fluorescent sensor based on BODIPY research can be stimulated and cultivated by this experiment. Furthermore, the experiment involves the knowledge of organic chemistry, instrumental analysis and applied spectroscopy, which can be used to improve students' experimental skills, comprehensive and innovative abilities. Thus, it is recommended to be included in the advanced comprehensive chemical experiment course.