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显微镜下经鼻-蝶窦入路术中脑脊液鼻漏的处理
引用本文:高俊,姚勇,李桂林,尹振明,邓侃,魏俊吉,李永宁,王任直.显微镜下经鼻-蝶窦入路术中脑脊液鼻漏的处理[J].中国微侵袭神经外科杂志,2010,15(2):62-64.
作者姓名:高俊  姚勇  李桂林  尹振明  邓侃  魏俊吉  李永宁  王任直
作者单位:北京协和医学院,北京协和医院神经外科,中国医学科学院,100730
摘    要:目的探讨显微镜下经鼻-蝶窦入路术中脑脊液鼻漏的处理方法。方法回顾性分析21例显微镜下经鼻-蝶窦入路术中发生脑脊液鼻漏的临床资料。鞍结节脑膜瘤1例,脊索瘤1例,垂体腺瘤19例。在切除肿瘤后均采用人工硬脑膜-明胶海绵-蛋白生物胶方法重建颅底硬膜,并辅以碘仿纱条填塞蝶窦腔。结果术后随访3个月~1年,无脑脊液鼻漏发生20例,发生可疑脑脊液鼻漏1例,保守治疗康复。结论即使手术导致颅底骨质、硬膜缺损明显,重建颅底硬膜辅以碘仿纱条填塞蝶窦腔,仍可有效预防术后脑脊液鼻漏的发生。

关 键 词:脑脊液鼻漏  颅底  经鼻-蝶窦手术

Management of intraoperative cerebrospinal fluid leakage in the microsurgery via a transnasal transsphenoidal approach
Gao Jun,Yao Yong,Li Guilin,et al.Management of intraoperative cerebrospinal fluid leakage in the microsurgery via a transnasal transsphenoidal approach[J].Chinese Journal of Minimally Invasive Neurosurgery,2010,15(2):62-64.
Authors:Gao Jun  Yao Yong  Li Guilin  
Affiliation:Gao Jun,Yao Yong,Li Guilin,et al. Department of Neurosurgery,Peking Union Medical College Hospital,Chinese Academy of Medicine Sciences & Peking Union Medical College,Beijing 100730,China
Abstract:Objective To explore the management of intraoperative cerebrospinal fluid leakage in the microsurgery via transnasal transsphenoidal approach. Methods The clinical data of 21 patients with intraoperative cerebrospinal fluid leakage in the microsurgery via transnasal transsphenoidal approach were analyzed retrospectively. There was tuberculum sellae meningioma in 1 case, chordoma in 1 and pituitary adenomas in 19. After the resection of the tumor, synthetic dural substitute, gelatin sponge and protein glue w...
Keywords:cerebrospinal fluid rhinorrhea  skull base  transnasal transsphenoidal microsurgery  
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