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苏艾冰精油外用对小鼠抗缺氧能力的影响
作者姓名:魏珍珍  方晓艳  白明  苗明三  樊帅珂
作者单位:河南中医药大学,郑州,450046,中国
基金项目:国家中医药管理局中医药标准化专项项目(No.2017-149-11),河南省产学研合作项目(No.182107000029)
摘    要:目的:探讨一种苏艾冰精油外用对小鼠抗缺氧能力的影响。方法:通过建立小鼠常压密闭缺氧模型、减压缺氧模型及异丙肾上腺素致小鼠缺氧模型,将苏艾冰精油涂抹于小鼠头面部、胸部,涂精油后放置于密闭环境中,记录小鼠的生存时间,以蒸馏水作为空白对照组,观察苏艾冰精油对小鼠抗缺氧能力的影响。结果:苏艾冰精油可显著延长常压密闭缺氧、减压缺氧、异丙肾上腺素缺氧小鼠的活存时间(P<0.01)。结论:苏艾冰精油可显著提高机体的耐缺氧能力。

关 键 词:苏艾冰精油  缺氧模型  异丙肾上腺素  芳香疗法  

Effects of Suaibing Essential Oil on Anti-Hypoxia Ability of Mice
Authors:WEI Zhen-zhen  FANG Xiao-yan  BAI Ming  MIAO Ming-san  FAN Shuai-ke
Affiliation:Henan University of Chinese Medicine,Zhengzhou,450046,China
Abstract:Objective:To investigate the effect of Suaibing essential oil on the antihypoxia ability of mice. Methods:Through the establishment of mice hypoxia model under normal pressure,hypoxia model under reduced pressure and mice hypoxia model induced by isoproterenol,Suaibing essential oil was applied to the head,face and chest of mice. After being applied with essential oil,the mice were placed in a closed environment. The survival time of mice was recorded,and distilled water was used as a blank control group to observe the effect of SuAibing essential oil on anti-hypoxia ability of mice. Results:The experimental results show that Suaibing essential oil can significantly prolong the survival time of normal pressure sealed hypoxia,hypobaric hypoxia,and isoproterenol hypoxic mice(P<0.01). Conclusion:Suaibing essential oil can significantly improve the body’s hypoxia tolerance.
Keywords:Suaibing essential oil  hypoxia model  isoproterenol  aromatic therapy  
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