| 反相高效液相色谱法测定双甲五灵胶囊中的五味子乙素 |
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| 引用本文： | 程建峰,周瑾,刘梅,张军武,赵亮. 反相高效液相色谱法测定双甲五灵胶囊中的五味子乙素[J]. 中国药房, 2003, 14(11): 686-687 |
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| 作者姓名： | 程建峰 周瑾 刘梅 张军武 赵亮 |
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| 作者单位： | 第四军医大学唐都医院药剂科,西安市,710038 |
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| 摘 要： | 目的 :以反相高效液相色谱法测定双甲五灵胶囊中五味子的有效成分五味子乙素的含量。方法 :色谱柱为YWGC18 柱(4 6mm×250mm ,10μm ) ,流动相为甲醇 -水 (72∶28) ,检测波长为254nm。结果 :五味子乙素在0 0207～0 4130mg/ml浓度范围内线性关系良好 (r=0 9999) ,平均回收率为97 68 % ,RSD=1 85 %。结论 :本方法简便、稳定 ,测定结果准确 ,能有效地控制该制剂的质量。
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| 关 键 词： | 双甲五灵胶囊 五味子乙素 反相高效液相色谱法 |
| 文章编号： | 1001-0408(2003)11-0686-02 |
| 修稿时间： | 2003-04-01 |
Determination of γ- schizandrin in Shuangjia Wuling Capsules by RP- HPLC |
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| CHENG Jianfeng,ZHOU Jin,LIU Mei,ZHANG Junwu,ZHAO Liang. Determination of γ- schizandrin in Shuangjia Wuling Capsules by RP- HPLC[J]. China Pharmacy, 2003, 14(11): 686-687 |
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| Authors: | CHENG Jianfeng ZHOU Jin LIU Mei ZHANG Junwu ZHAO Liang |
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| Abstract: | OBJECTIVE:To determine the content of γ-schizandrin,one of the effective ingredients,in Shuangjia Wuling capsules METHODS:The RP-HPLC method was performed with YWG C18 column(4 6mm×250mm) The mobile phase consisted of methanol-water(72∶28) The detecting wavelength was 254nm RESULTS:The calibration curve for γ-schizandrin was linear in the range of 0 0 207～0 4 130mg/ml(r=0 9 999) The average recovery was 97 68% with RSD=1 85% CONCLUSION:The method is simple,rapid and reliable for quality control of the capsules |
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| Keywords: | Shuangjia Wuling capsule γ-schizandrin RP-HPLC |
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