综合干预对极低出生体重儿婴儿期生长发育的影响

目的：：探讨出院后早期综合干预对极低出生体重儿婴儿期体格和运动发育的影响。方法：以我院35例极低出生体重儿为干预组，以同期40例正常健康足月儿为对照组，干预组早期给予系统化的综合干预。分别于3月龄、6月龄、9月龄、12月龄时观察两组体格发育和运动发育情况。结果：干预组极低出生体重儿在出生、3月龄、6月龄时体格和运动发育均明显落后于对照组足月儿(P＜0.05)。9月龄时，极低出生体重儿身长、体重和运动发育已达足月儿水平(P＞0.05)；但干预组极低出生体重儿的头围仍小于对照组足月儿(P＜0.05)。12月龄时，极低出生体重儿的体格发育和运动发育均已达足月儿水平(P＞0.05)。结论：出院后早期对极低出生体重儿实施综合干预，能使极低出生体重儿在婴儿期完成体格和运动发育的追赶生长，达到正常发育的水平。

INFLUENCES OF COMPREHENSIVE INTERVENTION ON GROWTH AND DEVELOPMENT OF VERY LOW BIRTH WEIGHT INFANT IN INFANCY

[ABSTRACT]Objective: To explore the influences of early comprehensive intervention out of hospital on physical and motor development of very low birth weight infants (VLBWI).Methods: 35 VLBWI that hospitalized in our hospital were used as intervention group, 40 healthy full term infants as control group. The infants in intervention group were given early systemic comprehensive intervention. The physical and motor developments of infants in 2 groups were respectively observed at 3 months, 6 months, 9 months and 12 months age.Results: The physical and motor development of VLBWI at birth, 3 months and 6 months age were obviously lagged behind healthy full term infants(P<0.05). At 9 months age, the height, body weight and motor development of VLBWI already reached healthy full term infants(P>0.05); but the head circumference of VLBWI was still less than that of healthy full term infants (P<0.05). At 12 months age, the physical and motor development of VLBWI all reached healthy full term infants(P>0.05).Conclusions: Early comprehensive intervention out of hospital in infancy can stimulate the growth potential of VLBWI and help them achieve normal developmental level.