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直肠癌转移与癌组织微血管密度的关系
引用本文:朱州,王卫星,黄顺荣. 直肠癌转移与癌组织微血管密度的关系[J]. 微循环学杂志, 2007, 17(2): 43-44
作者姓名:朱州  王卫星  黄顺荣
作者单位:1. 武汉大学人民医院普通外科,武汉,430060
2. 广西壮族自治区人民医院胃肠外科
摘    要:目的:分析直肠癌组织的微血管密度(MVD)变化及其对癌转移的临床诊断价值。方法:采用免疫组织化学法,对72例手术切除直肠癌组织标本进行微血管标记;在光学显微镜下测定其MVD。将所有患者的临床及追踪随访资料与其手术标本的MVD数据进行统计分析。结果:有转移直肠癌组织的MVD高于无转移者(106.12±32.18vs84.26±27.13),差异有非常显著性意义。结论:直肠癌组织的MVD增加对诊断癌转移有一定的临床价值。

关 键 词:直肠癌  微血管密度  转移
文章编号:1005-1740(2007)02-0043-02
收稿时间:2007-03-06
修稿时间:2007-03-062007-04-08

Relationship Between Rectal Cancer Metastasis and Microvessel Density of Tissues in Rectal Cancer
Zhu Zhou,Wang Weixing,Huang Shunrong. Relationship Between Rectal Cancer Metastasis and Microvessel Density of Tissues in Rectal Cancer[J]. Chinese Journal of Microcirculation, 2007, 17(2): 43-44
Authors:Zhu Zhou  Wang Weixing  Huang Shunrong
Abstract:Objective: To investigate the change of microvessel density (MVD) in the tissue of rectal cancer and its clinical value to prognosticate metastasis of the cancer. Method: Immuno-histo-chemistry assay was used to sign the microvessels in the resection samples from 72 cases with rectal cancer. MVD was counted using the microscope. Clinical data, follow-up data and MVD of all the cases were statistically analyzed. Results: MVD was significantly higher in samples from the cases with metastasis than that from the cases without metastasis (106.12±32.18 vs 84.26±27.13).Conclusion: MVD in the tissue of rectal cancer has diagnostic significance on metastasis of the cancer.
Keywords:Rectal cancer  Microvessel density  Metastasis
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