Normetanephrine and metanephrine oxidized by both types of monoamine oxidase |
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| Authors: | O. Suzuki T. Matsumoto |
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| Affiliation: | (1) Department of Legal Medicine, Hamamatsu University School of Medicine, 431-31 Hamamatsu, (Japan);(2) Division of Oncology, First Department of Surgery, Nagoya University School of Medicine, 466 Nagoya, (Japan) |
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| Abstract: | Summary Both normetanephrine and metanephrine were found to be oxidized by both types of monoamine oxidase in mouse liver mitochondria. Both Km and Vmax values of type B MAO for both substrates were higher than those of type A MAO, which caused the shift of inhibition curves with clorgyline and deprenyl according to the increase in substrate concentration. |
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| Keywords: | Mouse liver mitochondria normetanephrine metanephrine monoamine oxidase |
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