| 表皮生长因子受体酪氨酸激酶抑制剂的研究进展 |
| |
| 引用本文： | 王章桂,孙国平. 表皮生长因子受体酪氨酸激酶抑制剂的研究进展[J]. 现代肿瘤医学, 2007, 15(12): 1857-1860 |
| |
| 作者姓名： | 王章桂 孙国平 |
| |
| 作者单位： | 安徽医科大学第一附属医院肿瘤科,安徽,合肥,230031 |
| |
| 摘 要： | 表皮生长因子受体(epidermal growth factor receptor,EGFR)在细胞的信号转导、细胞增殖和分化中发挥着重要的作用,对多种肿瘤的发生和发展也具有重要影响,抑制该受体活性可以有效抑制肿瘤的生长。以此为靶点的抗肿瘤药物的开发,在多种肿瘤治疗中取得了令人鼓舞的疗效。
|
| 关 键 词： | 表皮生长因子受体 酪氨酸激酶抑制剂 抗肿瘤 |
| 文章编号： | 1672-4992-(2007)12-1857-04 |
| 修稿时间： | 2007-01-17 |
The development of the epidermal growth factor receptor tyrosine kinase inhibitor |
| |
| WANG Zhang-gui,SUN Guo-ping. The development of the epidermal growth factor receptor tyrosine kinase inhibitor[J]. Journal of Modern Oncology, 2007, 15(12): 1857-1860 |
| |
| Authors: | WANG Zhang-gui SUN Guo-ping |
| |
| Abstract: | Epidermal growth factor receptor plays an important role in the cell signal transduction,proliferation and differentiation and affects the development of malignant tumors.Blocking the EGFR can inhibit the growth of neoplasm effectively.The development of anti-cancer drugs that target EGFR have acquired an exciting curative effect. |
| |
| Keywords: | epidermal growth factor receptor tyrosine kinase inhibitor anti-tumor |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
