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| 真核细胞蛋白质翻译起始研究进展 | |
| 引用本文： | 周培,杨力,陈佳,李伯良,赵学明,张耀洲.真核细胞蛋白质翻译起始研究进展[J].浙江理工大学学报,2004,21(4):312-315. |
| 作者姓名： | 周培 杨力 陈佳 李伯良 赵学明 张耀洲 |
| 作者单位： | 1. 天津大学化工学院,天津,300072 2. 中国科学院上海生化及细胞研究所,上海,200031 3. 浙江理工大学生物化学研究所,浙江杭州,310033 |
| 摘 要： | 在大量有关机制的研究基础上,针对真核蛋白质翻译起始,提出了核糖体沿mRNA滑动识别翻译起始位点的机制和核糖体从mRNA内部识别翻译起始位点的机制. |
| 关 键 词： | 真核细胞 蛋白质 翻译起始 |
| 文章编号： | 1009-4741(2004)04-0312-04 |
| 修稿时间： | 2004年6月14日 |
Progress of Translation Initiation Research about Eukaryotes Cell |
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| ZHOU Pei,YANG Li,CHEN Jai,LI Bo-liang,ZHAO Xue-ming,ZHANG Yao-zhou.Progress of Translation Initiation Research about Eukaryotes Cell[J].Journal of Zhejiang Sci-tech University,2004,21(4):312-315. | |
| Authors: | ZHOU Pei YANG Li CHEN Jai LI Bo-liang ZHAO Xue-ming ZHANG Yao-zhou |
| Affiliation: | ZHOU Pei~1,YANG Li~2,CHEN Jai~2,LI Bo-liang~2,ZHAO Xue-ming~1,ZHANG Yao-zhou~3 |
| Abstract: | The emphasis of translation initiation research in eukaryotes mainly lies in two aspects, which is the binding process of ribosome to mRNA and the recognition of the initiation sites.There are two types of binding process of the eukaryotes during the translation initiation. The ribosome binds to the 5'm7G cap, or directly enters the internal ribosome enter site (IRES).Some researchers also reported that eukaryotes can take both the AUG and AUG-cognate as start codons in translation initiation. Based on the research of the translation initiation mechanism, the scanning model and the internal initiation of translation model are brought forward. All these researches and hypothesis on the mechanism enrich the understanding of the translation initiation of eukaryotes. |
| Keywords: | Eukaryotes Protein Translation initiation |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |
