广州地区妇女跟骨定量超声骨质测量308例分析

目的探讨广州地区妇女骨质变化规律,为骨质疏松防治提供科学依据。方法采用法国DMS公司UBIS5000型超声骨密度/骨质量测量仪对广州地区308例妇女进行跟骨骨质测量及评估。结果本组资料各参数中,超声振幅衰减平均值在绝经期由(66.9±5.6)dB/MHz急剧降至(65.0±4.5)dB/MHz(P<0.01),而绝经后早期下降相对平缓(P>0.05),但老年期开始又呈明显递减(P<0.01)。超声传播速度值在骨峰值出现后随年龄增加而有规律地递减,进入绝经期后呈急剧递减(P<0.01),但81岁以上时则下降不再显著(P>0.05)。骨硬度指数值在绝经期开始即急剧递减(P<0.01),且下降幅度较大、敏感、直观。结论定量超声骨质测量仪不仅可以提供反映骨量的指标,而且可以对骨结构进行评估。

Quantitative ultrasound at the calcaneus in 308 women from Guangzhou area

Aim To study the changes of bone by quantitative ultrasourd(QUS) in women in Guangzhouand provide scientific basis for prevention and treatment of osteoporosis(OP). Methods Bone status was established using measurements at the calcaneus by QUS(DMS, French), which measures speed of sound , broadband ultrasound attenuation BUA(dB/MHz)] and stiffness index in 308 women from Guangzhou area.Results In menopause and aged women, BUA showed a significantly decrease(P< 0.01), whereas it decreased only slightly in early postmenopausal women(P >0.05). After the peak of BMD, SOS showed a stepwise decline, and significantly decrease in menopause (P< 0.01), but no significant over eighties( P >0.05) . In contrast, STI significantly decreased from the menopause, was a better indicator than BUA or SOS. Conclusion QUS of bone is a promising technique in assessing bone microarchitecture in addition to bone mass, which is cheaper, and easier to use than the more established method of bone densitometry.