银离子愈邦敷料联合银锌霜治疗重症剥脱性药疹疗效评价

目的:评价新型敷料银离子愈邦联合银锌霜应用于重症药疹大面积剥脱性创面愈合的疗效。方法:42例患者随机分为观察组与对照组,每组各21例。观察组采用愈邦与银锌霜,对照组采用油纱与金霉素眼膏。观察创面愈合时间、患者疼痛度,换药次数。结果:观察组创面愈合时间平均10.10±2.88天,对照组平均13.44+3.16天,差异有极显著统计学意义(P0.01)。观察组换药时疼痛总VAS评分为2.73+1.15分,对照组3.58+2.11分,差异有极显著统计学意义(P0.01);观察组换药次数平均2.47±1.15次,对照组平均4.45±1.22次,差异有极显著统计学意义(P0.01)。结论:愈邦敷料用于重症药疹大面积剥脱性皮损换药疗效肯定。

Assessment of Yubang in combination with silver-zinc ointment promote healing of the desquamation lesion of drug-induced eruption

Objective： To assess the clinical efficacy of Yubang in combination with silver-zinc ointment on exfoliative lesion of drug-induced eruption. Methods： Forty-two patients were divided into two groups： 21 patients in each group. The patients in experimental group were treated with Yubang in combination with silver-zinc ointment and those in control group were treated with oily gauze in combination with aureomycin eye ointment. The healing time of skin lesion, the degree of pain and the times of changing dressing were assessed. Results：The average healing time of skin lesions in experimental group was 10.10±2.88 days, which was less than that in the controls （13.44±3.16 days） （P〈0.01）. The total VAP score in the treatment group was 2.73 ±1.15, which was significantly lower than that in the control group （3.58±2.11） （P〈0.01）. The average times of changing dressing was 2.47±1.15, which were less than that in the controls （4.45±1.22） （P〈0.01）. Conclusion： Yubang in combination with silver-zinc ointment was effective in the treatment of exfoliative le-sions of drug-induced eruption.