| 头孢菌素C钠溶液膜分离工艺的研究 |
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| 引用本文： | 鲍建芝,李杰,张晓艳,陈尧,曹云峰,卢华.头孢菌素C钠溶液膜分离工艺的研究[J].膜科学与技术,2007,27(1):82-84,88. |
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| 作者姓名： | 鲍建芝 李杰 张晓艳 陈尧 曹云峰 卢华 |
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| 作者单位： | 石家庄制药集团,石家庄,050051 |
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| 摘 要： | 以头孢菌素C钠盐的水溶液为对象设计实验,考察了板式膜的膜通量和溶质透过率的衰减现象,以及钠离子对膜的影响.研究结果表明,衰减的主要原因是膜表面吸附钠离子以及在膜表面形成浓差极化层;原液浓度影响膜通量是间接的;此外在宏观表现如原液浓度高、膜的处理量大、处理时间长和钠离子含量高都将加剧膜通量和溶质透过率的衰减.在实际应用中需考虑这些因素.
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| 关 键 词： | 膜 通量 衰减 污染 溶质透过率 |
| 文章编号： | 1007-8924（2007）01-0082-03 |
| 修稿时间： | 2005-04-202005-05-29 |
Ultrafiltration process of cephalosporin C sodium solution |
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| BAO Jianzhi,LI Jie,Zhang Xiaoyan,CHEN Yao,CAO Yunfeng,LU Hua.Ultrafiltration process of cephalosporin C sodium solution[J].Membrane Science and Technology,2007,27(1):82-84,88. |
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| Authors: | BAO Jianzhi LI Jie Zhang Xiaoyan CHEN Yao CAO Yunfeng LU Hua |
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| Affiliation: | Shijiazhuang Pharmaceutical Group Co. , Ltd. , Shijiazhuang 050051, China |
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| Abstract: | The declines of both the UF membrane flux and solute permeation coefficient,and the influence of sodium ions on the membrane performance during the ultrafiltration process of cephalosprin C sodium solution were studied.It is shown that the main reasons of the declines are the adsorption of sodium ions and concentration polarization on the membrane surface.The influence of feed concentration on membrane flux is indirectly.The attenuations of both membrane flux and solute permeation coefficient are concerned with the high feed concentration,large volume production,long time run,and high content of sodium ion. |
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| Keywords: | membrane flux decline fouling solute permeation coefficient |
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