结缔组织病的肺部HRCT表现

目的评价结缔组织病肺部病变的HRCT表现。方法分析144例临床确诊为结缔组织病的肺部HRCT表现，观察病变的异常表现及分布特点。结果144例结缔组织病的肺部HRCT最常见异常表现为小叶间隔增厚（107例，74．3％）、胸膜病变（88例，61．1％）、磨玻璃密度影（65例，45．1％）、胸膜下线（49例，34．0％）；而蜂窝样变、心包病变最少见。肺内病变主要分布在下肺区、外周部。在RA、SLE、PM—DM二组间，小结节样影更常见于SLE（37．8％，P=0．003）。结论HRCT是评价结缔组织病肺部损害的敏感方法，对指导临床治疗、判断预后有重要价值。

High-resolution CT finding of lung diseases with connective tissue diseases

Objective To evaluate the HRCT findings of lung diseases in patients with connective tissue diseases. Methods 144 patients with connective tissue diseases confirmed clinically were analysis by HRCT to evaluate the characteristic HRCT manifestations of the lesions and its distributions in the lungs. Results In these 144 cases interlobular spetal thickening （ 107cases,74.3% ）, pleural abnormalities （88cases, 61.1% ）, ground -glass opacity （65 cases, 45.1% ）, and subpleural line （49 case, 34.0% ）were the most common abnormalities on HRCT, whereas honeycombing and cardial abnormalities were less common. The lesions of the lung predominate at the lower lung zones and in the periphery. Among RA, SLE, and DM-PM groups, micronodule-like shadowes were more common in SLE （37.8% , P = 0. 003 ）. Conclusion HRCT is a sensitive technique in assessing lung diseases associated with connective tissue diseases , which can offers a more valuable information to clinical treatment and prognosis.