Synthesis, structural properties and insulin-enhancing potential of bis(quercetinato)oxovanadium(IV) conjugate |
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| Authors: | Shukla Ruchi Barve Vivek Padhye Subhash Bhonde Ramesh |
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| Affiliation: | National Centre for Cell Science, Pune University Campus, Pune 411007, India. |
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| Abstract: | An oxovanadium complex of quercetin (2), exhibits highly potent insulin-enhancing activity in streptozotocin-induced diabetic mice. It also mimics mitogenic potential of insulin as evaluated by [H(3)]thymidine uptake assay making an effective, orally active insulin-enhancing agent for the treatment of both type 1 and type 2 diabetes without any noticeable toxic effects. |
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