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聪灵胶囊对实验性血小板性血栓形成抑制作用的初步研究
引用本文:荣本兵,李作孝,肖顺汉,杨思进,唐灿.聪灵胶囊对实验性血小板性血栓形成抑制作用的初步研究[J].泸州医学院学报,2007,30(3):176-177.
作者姓名:荣本兵  李作孝  肖顺汉  杨思进  唐灿
作者单位:1. 泸州医学院附属医院神经内科,四川泸州,646000
2. 泸州医学院附属医院药学院,四川泸州,646000
摘    要:目的:探讨聪灵胶囊抑制血小板凝集、抗血栓形成的作用.方法:建立动一静脉旁路血栓形成模型,喜得镇作为阳性对照药,研究聪灵胶囊对大鼠血栓形成的影响.结果:聪灵胶囊高中剂量组及阳性对照组的血栓湿重均明显降低,与空白对照组相比,具有显著性差异(P<0.05),聪灵胶囊高中剂量组与阳性对照组相比无显著性差异(P>0.05).结论:聪灵胶囊具有一定程度的抑制血小板凝集、抗血栓形成的作用.

关 键 词:聪灵胶囊  血栓形成
文章编号:1000-2669(2007)3-0176-02
修稿时间:2006-11-17

PRELIMZNARY STUDY OF DEPRESSANT EFFECT OF CONGLING CAPSULE ON PLATELET THROMBOSIS
Rong Benbing, et al.PRELIMZNARY STUDY OF DEPRESSANT EFFECT OF CONGLING CAPSULE ON PLATELET THROMBOSIS[J].Journal of Luzhou Medical College,2007,30(3):176-177.
Authors:Rong Benbing  
Affiliation:Department of Neurology, The Affiliated Hospital of Luzhou Medical College
Abstract:Objective: To study the inhibition of platelet aggregation and thrombosis by Congling Capsule.Methods:Thrombosis model was produced by putting a silk filament into plastic tube then inserting it between right common carotid artery and left external jugular vein, with hydergine as control. Wet weight of thrombus was measured .Results: Compared with the non-treatment group,the wet weight of thrombus in hydergine treatment group and high and medium dosage Congling Capsule groups was significanly declined (P<0.05).There was no significant difference between high or medium dosage Congling Capsule treatment group and hydergine treatment group(P>0.05).Conclusion: Congling Capsule is an effective Chinese herbal preparation for inhibition of platelet aggregation and thrombosis.
Keywords:Congling Capsule  Thrombosis
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