| 质子磁共振波谱对帕金森病的诊断价值 |
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| 引用本文： | 王大力,刘昊,王坚,蒋雨平. 质子磁共振波谱对帕金森病的诊断价值[J]. 临床神经病学杂志, 2002, 15(4): 213-214 |
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| 作者姓名： | 王大力 刘昊 王坚 蒋雨平 |
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| 作者单位： | 1. 063000,唐山,华北煤炭医学院附属医院神经科
2. 上海华山医院神经科 |
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| 摘 要： | 目的 探讨质子磁共振波谱 (1 H MRS)对帕金森病 (PD)的诊断价值。方法 通过对 1 5例PD患者和 5名年龄匹配健康对照者双侧基底节区1 H MRS观测 ,分析其基底节区N 乙酰天冬氨酸 /肌酸 (NAA/Cr)和胆碱 (Cho) /Cr比值的变化。结果 PD患者基底节区NAA/Cr含量显著低于对照组 (P <0 0 5)。结论 1 H MRS是研究PD患者基底节区神经元是否遭受破坏的一种无创技术
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| 关 键 词： | 帕金森病 磁共振波谱分析 基底节区 诊断 |
| 文章编号： | 1004-1648(2002)04-0213-02 |
| 修稿时间： | 2002-01-28 |
Diagnostic value on proton magnetic resonance spectroscopy of idiopathic Parkinson''''s disease |
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| Wang Dali,Liu Hao,Wang Jian,et al.. Diagnostic value on proton magnetic resonance spectroscopy of idiopathic Parkinson''''s disease[J]. Journal of Clinical Neurology, 2002, 15(4): 213-214 |
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| Authors: | Wang Dali Liu Hao Wang Jian et al. |
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| Affiliation: | Wang Dali,Liu Hao,Wang Jian,et al.Department of Neurology,Affiliated Hospital of Huabei Coal Medical College,Tangshan,063000 |
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| Abstract: | Objective To explore the diagnostic value on proton magnetic resonance spectroscopy ( 1H MRS) of idiopathic Parkinson's disease (PD).Methods 1H MRS of both basal ganglia was observed in 15 patients with PD and 5 healthy age matched controls.The change of NAA/Gr and Cho/Cr ratio in basal ganglia were analysed.Results The PD group showed a significant reduction in the NAA/Cr ratio compared with the NAA/Cr ratio from the control group ( P <0 05).Conclusion 1H MRS is a noninvasive technique that can provide useful information on neuronal loss in the basal ganglia of the patients with PD. |
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| Keywords: | PD 1H MRS Basal ganglia |
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