| 急性胰腺炎患者血浆内皮素及D-二聚体水平变化研究 |
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| 引用本文： | 李玲,尹苹,徐克前,伍炜.急性胰腺炎患者血浆内皮素及D-二聚体水平变化研究[J].检验医学与临床,2013(11):1411-1412. |
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| 作者姓名： | 李玲 尹苹 徐克前 伍炜 |
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| 作者单位： | [1]中南大学湘雅医学院检验系,湖南长沙410000 [2]湘乡市人民医院普外科,湖南湘乡411400 |
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| 摘 要： | 目的探讨血浆内皮素(ET)和D-二聚体(D-D)对急性胰腺炎(AP)严重程度的诊断价值。方法将90例确诊AP患者分为重症AP(SAP)组42例和轻症AP(MAP)组48例,另将40例健康者纳入对照组,检测并比较血浆ET、D-D浓度。结果 SAP组ET、D-D浓度高于MAP组和对照组(P<0.05),且随着APACHEⅡ评分升高,ET、D-D浓度升高。结论血浆ET和D-D检测对AP病情严重程度有诊断价值。
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| 关 键 词： | 急性胰腺炎 内皮素 D-二聚体 病情 |
Changes of serum endothelin and D-dimer level in patients with acute pancreatitis |
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| LI Ling,YIN Ping,XU Ke-qian△,WU Wei.Changes of serum endothelin and D-dimer level in patients with acute pancreatitis[J].Laboratory Medicine and Clinic,2013(11):1411-1412. |
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| Authors: | LI Ling YIN Ping XU Ke-qian△ WU Wei |
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| Affiliation: | 1.Department of Clinical Laboratory,Xiangya Medicine School,Central South University,Changsha,Hunan 410000,China;2.Department of General Surgery,the People′s Hospital of Xiangxiang,Xiangxiang,Hunan 411400,China) |
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| Abstract: | Objective To investigate the diagnostic significance of plasma endothelin（ET） and D-dimer（D-D） for severity of acute pancreatitis（AP）.Methods Plasma ET and D-D concentration were detected and compared in 90 cases of AP,including 42 cases for severe AP（SAP） group and 48 cases for mild AP（MAP） group,and 40 cases of healthy subjects（control group）.Results Compared with control group and MAP group,the plasma ET and D-D level were elevated in SAP group（P0.05）.With the increasing of APACHEⅡscore,the content of ET and D-D also increased.Conclusion Detection of plasma ET and D-D concentration might have judgement value to severity of AP. |
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| Keywords: | acute pancreatitis endothelin D-dimer pathogenetic condition |
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