| 乳腺良恶性病变的磁共振T2*W首过灌注成像与血管生成相关性研究 |
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| 引用本文： | Xiaoming Zhuang,Bing Zhang,Bin Zhu,Min Xie,Xiangshan Fan,Fanqing Meng.乳腺良恶性病变的磁共振T2*W首过灌注成像与血管生成相关性研究[J].中德临床肿瘤学杂志,2007,6(4):357-360. |
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| 作者姓名： | Xiaoming Zhuang Bing Zhang Bin Zhu Min Xie Xiangshan Fan Fanqing Meng |
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| 作者单位： | [1]Department of General Surgery, the Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China [2]Department of Radiology, the Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China [3]Department of Pathology, the Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China |
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| 基金项目： | Supported by a grant from the Medicine Scientific Development Foundation of Nanjing （No. zkx05021）. |
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| 摘 要： | Objective： To study the diagnostic value of T2^＊-weighted first-pass perfusion imaging in breast tumors. Methods： We analyzed the magnetic resonance imaging （MRI） information along with the pathological and immunohistochemistry results. Magnetic resonance imaging was performed in 28 patients with breast tumor. The time to signal intensity curves were generated according to the T2^＊-weighted first-pass perfusion imaging. The curve＇s maximal signal intensity drop rate and maximal signal intensity decrease time were analyzed and compared with the pathological diagnoses after surgery. Results： Malignant breast lesions showed higher maximal signal intensity drop rate （44.69% ± 17.07 vs. 17.22% ±7.49, P 〈 0.001） than benign lesions, but there was no significant difference of maximal signal decrease time between those two lesions （23.94 s ± 4.92 vs. 20.02 s ± 6.83, P 〉 0.05）. Conclusion： The T2^＊-weighted first-pass perfusion imaging has enough sensitivity and specificity in breast tumor diagnosis.
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| 关 键 词： | 乳腺良恶性病变 磁共振T2W 首过灌注成像 血管生成 |
| 收稿时间： | 10 February 2007 |
| 修稿时间： | 2007-02-10 |
Application of T2*-weighted first-pass perfusion imaging in the diagnosis of breast tumors |
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| Xiaoming?Zhuang,Bing?Zhang,Bin?Zhu,Min?Xie,Xiangshan?Fan,Fanqing?Meng.Application of T2*-weighted first-pass perfusion imaging in the diagnosis of breast tumors[J].The Chinese-German Journal of Clinical Oncology,2007,6(4):357-360. |
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| Authors: | Xiaoming Zhuang Bing Zhang Bin Zhu Min Xie Xiangshan Fan Fanqing Meng |
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| Affiliation: | Department of General Surgery, the Affiliated Drum Tower Hospital, Nanjing University Medical School Nanjing 210008, China ; Department of Radiology, the Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China ; Department of Pathology, the Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China |
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| Abstract: | Objective To study the diagnostic value of T2*-weighted first-pass perfusion imaging in breast tumors.
Methods We analyzed the magnetic resonance imaging (MRI) information along with the pathological and immunohistochemistry results.
Magnetic resonance imaging was performed in 28 patients with breast tumor. The time to signal intensity curves were generated
according to the T2*-weighted first-pass perfusion imaging. The curve’s maximal signal intensity drop rate and maximal signal
intensity decrease time were analyzed and compared with the pathological diagnoses after surgery.
Results Malignant breast lesions showed higher maximal signal intensity drop rate (44.69% ± 17.07 vs. 17.22% ± 7.49, P < 0.001) than benign lesions, but there was no significant difference of maximal signal decrease time between those two lesions
(23.94 s ± 4.92 vs. 20.02 s ± 6.83, P > 0.05).
Conclusion The T2*-weighted first-pass perfusion imaging has enough sensitivity and specificity in breast tumor diagnosis.
Supported by a grant from the Medicine Scientific Development Foundation of Nanjing (No. zkx05021). |
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| Keywords: | breast tumor magnetic resonance imaging perfusion diagnosis |
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