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| SERS传感器间接检测蛋白质的研究进展 | |
| 引用本文： | 陈雷,刘毛毛,张永军,王雅新,韩晓霞,赵冰.SERS传感器间接检测蛋白质的研究进展[J].光谱学与光谱分析,2017,37(10):3094-3098. |
| 作者姓名： | 陈雷 刘毛毛 张永军 王雅新 韩晓霞 赵冰 |
| 作者单位： | 1. 吉林师范大学环境友好材料制备与应用教育部重点实验室，吉林 长春 130103 2. 吉林师范大学功能材料物理与化学教育部重点实验室，吉林 长春 130103 3. 吉林大学超分子结构与材料国家重点实验室，吉林 长春 130012 |
| 基金项目： | 国家自然科学基金项目，吉林省科技发展计划项目，吉林师范大学博士科研启动项目 |
| 摘 要： | 蛋白质在生命体中发挥着重要的作用，蛋白质的检测对于了解生命体系及在生物医学领域都有基础性的应用价值。表面增强拉曼光谱(SERS)技术对研究化学和生物传感应用前景很有优势，是由于其高灵敏度以及很好的选择性，并且已被运用于生物分子检测，特别是在蛋白质检测方面。综述了SERS探针技术用于蛋白质检验的研究现状，如免疫胶体金技术、基于纳米材料探针的SERS研究、基于酶促技术和基于试剂技术的蛋白质研究进展。 |
| 关 键 词： | SERS 蛋白质检测 免疫胶体金 拉曼活性纳米材料 酶促反应 试剂技术 |
| 收稿时间： | 2016-04-13 |
Indirect Protein Detection by Versatile SERS Sensors |
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| CHEN Lei,LIU Mao-mao,ZHANG Yong-jun,WANG Ya-xin,HAN Xiao-xia,ZHAO Bing.Indirect Protein Detection by Versatile SERS Sensors[J].Spectroscopy and Spectral Analysis,2017,37(10):3094-3098. | |
| Authors: | CHEN Lei LIU Mao-mao ZHANG Yong-jun WANG Ya-xin HAN Xiao-xia ZHAO Bing |
| Affiliation: | 1. Key Laboratory of Preparation and Application of Environmental Friendly Materials of Ministry of Education, Jilin Normal University, Changchun 130103, China 2. Key Laboratory of Functional Materials Physics and Chemistry of Ministry of Education, Jilin Normal University, Changchun 130103, China 3. State Key Laboratory of Supramolecular Structure and Meterials, Jilin University, Changchun 130012, China |
| Abstract: | Proteins are essential for living organisms because they are main components of the physiological metabolic pathways of cells.As an ultrasensitive technique,surface-enhanced Raman scatting (SERS)has been proved having a great potential in high throughput biomolecules detection,especially in proteins detection.In this paper,recent advances of the development of SERS probe technology were presented,such as immunogold-based method,Raman-active nanomaterial-based sensors,enzymat-ic-based sensors,and reagent-based sensors. |
| Keywords: | SERS Protein detection Immunogold Raman-active nanomaterial Reagent-based sensors Enzyme-catalyzed reac-tion |
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