| 单精子胞质内注射治疗严重男性不育和受精障碍102个周期的回顾性分析 |
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| 引用本文： | 林戈 唐正严 等. 单精子胞质内注射治疗严重男性不育和受精障碍102个周期的回顾性分析[J]. 湖南医科大学学报, 2001, 26(6): 502-504 |
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| 作者姓名： | 林戈 唐正严 等 |
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| 作者单位： | [1]中南大学湘雅医学院人类生殖工程研究室 [2]中南大学湘雅医院泌尿外科，长沙410078 |
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| 摘 要： | 回顾性分析从1998年1月至2000年12月在我室接受单精子显微授精治疗的共102个周期，以2000年2月为界，随为微操作技术，的改进和操作环境的改善，后阶段单精子显微注射的存活率（90＝6％），受精率（73．3％），胚胎发育率（97．3％）较前阶段（分别为68．8％，39．0％，78．7％）有显著提高。两阶段临床妊娠率分别为41．3％和21．4％，目前本室建立的单精子胞质内注射技术能有效地治疗临床严重男性不育和受精障碍。
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| 关 键 词： | 单精子胞质内注射 不育 男性 受精障碍 |
Retrospective analysis of 102 cycles of intracytoplasmic single sperm injection in treating severe male infertility and fertilization failure] |
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| G Lin,W Liu,C F Lu. Retrospective analysis of 102 cycles of intracytoplasmic single sperm injection in treating severe male infertility and fertilization failure][J]. Bulletin of Hunan Medical University, 2001, 26(6): 502-504 |
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| Authors: | G Lin W Liu C F Lu |
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| Affiliation: | Laboratory of Human Reproductive Engineering, Central South University, Changsha 410078, China. |
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| Abstract: | The aim of this study is to retrospectively analyze 102 cycles which received intracytoplasmic single sperm injection (ICSI) in our lab from January 1998 to December 2000. With the improvements of the technique and environment of the microscopic manipulation from February 2000, the survival rate (90.6%). fertilization rate (73.3%) and embryo development rate (97.3%) of the later stage were significantly higher than those of the previous (68.8%, 39.0%, 78.7% respectively). The clinical pregnancy rate reached a higher level (41.3% and 21.4% respectively). The ICSI technique established currently in our lab can effectively treat the severe male infertility and fertilization failure. |
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