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| 茶树油抗菌作用机理研究进展 | |
| 引用本文： | 陶凤云,张新妙,俞军,马润宇.茶树油抗菌作用机理研究进展[J].中国抗生素杂志,2006,31(5):261-266. |
| 作者姓名： | 陶凤云 张新妙 俞军 马润宇 |
| 作者单位： | 1. 北京联合大学生物化学工程学院,北京,100023;北京化工大学生命科学与技术学院,北京,100029 2. 北京化工大学生命科学与技术学院,北京,100029 3. 北京联合大学生物化学工程学院,北京,100023 |
| 摘 要： | 体外抗菌实验和临床数据表明，茶树油具有广谱抗菌活性，可望开发成为一种新的抗菌剂。茶树油以一种膜破坏剂的形式发挥作用，通过破坏膜结构，使细胞内钾离子泄漏，抑制细胞呼吸，刺激细胞自溶，导致细胞内电子密度物质损失，改变细胞形态学等。研究茶树油抗菌作用机理，有助于了解抗菌谱、毒性以及微生物耐药性的发展过程。 |
| 关 键 词： | 茶树油 抗菌活性 作用机理 膜破坏剂 |
| 文章编号： | 1001-8689(2006)05-0261-06 |
| 收稿时间： | 2005-10-12 |
| 修稿时间： | 2005-11-22 |
Progress on mechanism of antimicrobial activity of tea tree oil |
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| Tao Feng-yun,Zhang Xin-miao,Yu Jun,Ma Run-yu.Progress on mechanism of antimicrobial activity of tea tree oil[J].Chinese Journal of Antibiotics,2006,31(5):261-266. | |
| Authors: | Tao Feng-yun Zhang Xin-miao Yu Jun Ma Run-yu |
| Affiliation: | 1 Biochemical Engineering College of Beijing Union University, Beijing 100023; 2 College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029 |
| Abstract: | In vitro antimicrobial test and clinical data have showed that tea tree oil has a broad-spectrum of antimicrobial activity and it was possible to be developed a novel antibacterial agent. Tea tree oil acted as a membrane destructive agent. It destroyed membrane structure,induced celluler K+leakage,inhibited respiration,stimulated cell lysis,resulting the exudation of electron density material and also changing the cell morphology,etc. To study the mechanism of antimicrobial activity of tea tree oil would help to elucidate the activity spectrum and the mechanism of resistance development of microbes. |
| Keywords: | Tea tree oil Antimicrobial activity Mechanism of action Membrane destructive agent |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
