| 疏肝健脾冲剂免疫增强作用的实验研究 |
| |
| 引用本文： | 胡锡元,曾亚男,许国振,严启伟,彭连生.疏肝健脾冲剂免疫增强作用的实验研究[J].中国中西医结合消化杂志,2004,12(1):39-41. |
| |
| 作者姓名： | 胡锡元 曾亚男 许国振 严启伟 彭连生 |
| |
| 作者单位： | 1. 武汉市中医医院内科,武汉,430014
2. 武汉市中医医院中医药研究所 |
| |
| 摘 要： | 目的:研究疏肝健脾冲剂免疫增强的药理作用.方法:应用环磷酰胺造成小白鼠免疫功能低下模型,通过小鼠游泳实验、常压缺氧实验,观察试验药物对机体免疫功能及抗应激能力的影响.结果:疏肝健脾冲剂显著提高血清溶菌酶含量、半数溶血值、足垫肿胀厚度(P<0.05,<0.01),显著延长小鼠常压缺氧死亡时间和游泳时间(均P<0.01).结论:疏肝健脾冲剂具有提高机体免疫功能和抗应激能力的作用,为其治疗脾胃病的作用机制之一.
|
| 关 键 词： | 脾胃病 疏肝健脾冲剂 免疫增强 |
Experimental Study on Shugan Jianpi Granule in Reinforcing Immune Function |
| |
| HU Xiyuan,ZENG Yanan,XU Guozhen,et al TCM Internal.Experimental Study on Shugan Jianpi Granule in Reinforcing Immune Function[J].Chinese Journal of Integrated Traditional and Western Medicine on Digestion,2004,12(1):39-41. |
| |
| Authors: | HU Xiyuan ZENG Yanan XU Guozhen TCM Internal |
| |
| Affiliation: | HU Xiyuan,ZENG Yanan,XU Guozhen,et al TCM Internal Department,Wuhan Traditional Chinese Medical Hospital,Wuhan 430014 |
| |
| Abstract: | Objective: To study the pharmaceutical effect of Shugan Jianpi granule(SJG) in reinforcing immune function.Methods:Mice model of immune deficiency was induced by cyclophsphamide. Swimming and anoxia test under normal pressure were applied to observe the effect of SJG on immune function and resisting stress. Results :SJG increased serum lyzosome content, half hemolysis value, thickness of the swollen foot(P<0.05,P<0.01) and significantly prolonged both the time from anoxia to death and swimming time(P<0.01).Conclusion: SJG could improve immune function and resist stress, which might be one of its mechanisms in treating spleen and stomach diseases. |
| |
| Keywords: | spleen and stomach disease Shugan Jianpi granule reinforcing immune function |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
