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尿激酶治疗急性脑梗死临床观察
引用本文:霍岩,周淑芬,王海霞.尿激酶治疗急性脑梗死临床观察[J].医药世界,2009,11(5):101-102.
作者姓名:霍岩  周淑芬  王海霞
作者单位:黑龙江省牡丹江医学院第二附属医院老年病科,157009  
摘    要:目的:评价尿激酶(UK)治疗急性脑梗死(ACI)的临床疗效。方法:68例ACI患者随机分成治疗组和对照组。治疗组用UK15万U静脉推注,续以UK135万U60min内静脉滴注,对照组采用通常的治疗方案,评价治疗前和治疗后神经功能缺损评分。结果:治疗后神经功能缺损评分改善显著(P〈0.01)。结论:早期ACI采用UK治疗比常规治疗起效快、作用强、疗效好,并且安全、可靠。

关 键 词:尿纤溶酶原激活物/治疗应用  脑梗塞/药物疗法  急性病  人类

Clinical Observation of Treatment with Urokinase for Patients with Acute Cerebral Infaraction
HUO Yan,ZHOU Shu-fen,WANG Hai-xia.Clinical Observation of Treatment with Urokinase for Patients with Acute Cerebral Infaraction[J].Medicine World,2009,11(5):101-102.
Authors:HUO Yan  ZHOU Shu-fen  WANG Hai-xia
Affiliation:(Department of Geriatrics ,The Second Affiliated Hospital of Mudanjiang Medical University, Mudanjiang 157009, China)
Abstract:Objeetive:To evaluate efficacy of treatment with Urokinase(UK)for patients with acute cerebral infarction (ACI). Methods: 68 patients with ACI were randomly divided into therapy group and control group. Therapy group was given UK 150000 units Ⅳ injecting,and then 1 350 000 units Ⅳ dripping,control group with usual therapy method. Neurologic defect scoring system at admission and after treatment was evaluated. Results:To compare therapy group and control group, neurologic defect scoring was improved significantly (P〈0. 01),the execellent rate of therapy group was higher than the control group (P 〈0. 01). Conclusion:Treatment with UK for patients with acute cerebral infarction was a more effective than the conventional therapy,and was safe,reliable and convenient.
Keywords:Urinary Plasminogen Activator/therapeutic use  Brain Infarction/drug therapy  Acute Disease  Humans
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