| 染料木黄酮改善γ射线损伤小鼠抗氧化功能的作用 |
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| 引用本文： | 吴健全,金宏,许志勤,王先远,南文考,李培兵.染料木黄酮改善γ射线损伤小鼠抗氧化功能的作用[J].氨基酸和生物资源,2004,26(4):59-61. |
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| 作者姓名： | 吴健全 金宏 许志勤 王先远 南文考 李培兵 |
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| 作者单位： | 军事医学科学院卫生学环境医学研究所,天津,300050 |
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| 摘 要： | 用137Csγ射线照射雄性昆明小鼠,观察饲料中补充染料木黄酮(Genistein,Gen)对抗氧化功能的保护作用,探讨其抗辐射作用的机制。结果表明,Gen可以提高辐射小鼠脾和胸腺组织总抗氧化能力(T-AOC)、降低血清、肝脏和胸腺组织丙二醛(MDA)水平;显著提高辐射小鼠抗氧化功能。
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| 关 键 词： | 染料木黄酮 电离辐射 抗氧化 |
| 文章编号： | 1006-8376(2004)04-0059-03 |
| 修稿时间： | 2004年7月11日 |
Protective Effect of Genistein on Antioxidant Function of Irradiated Mice |
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| WU Jian-quan,JIN Hong,XU Zhi-qin,Wang Xian-yuan,Nan Wen-kao,Li Pei-bing.Protective Effect of Genistein on Antioxidant Function of Irradiated Mice[J].Amino Acids & Biotic Resources,2004,26(4):59-61. |
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| Authors: | WU Jian-quan JIN Hong XU Zhi-qin Wang Xian-yuan Nan Wen-kao Li Pei-bing |
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| Abstract: | Male mice were fed with feedstuff in which different does of genistein or normal diet were added for 2 weeks. Then the mice were irradiated once with 4.0 Gy γ-rays and the changes of their antioxidant function were observed. The T-AOC of mice exposed to radiation and genistein were increased in thymus and spleen, and their MDA concentration were decreased in serum、thymus and liver.The observations suggest that genistein has significant protective effects on antioxidant functions of irradiated mice. 氨基酸和生物资源 |
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| Keywords: | genistein radiation antioxidant function |
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