| 柴银口服液质量标准研究 |
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| 引用本文： | 史国生,谢强胜,李启艳,王玉团. 柴银口服液质量标准研究[J]. 中国药品标准, 2014, 15(5): 343-347 |
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| 作者姓名： | 史国生 谢强胜 李启艳 王玉团 |
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| 作者单位： | 山东省食品药品检验所,济南250101 |
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| 摘 要： | 目的：修订完善柴银口服液质量标准。方法：用薄层鉴别主药苦杏仁；用高效液相色谱法测定柴胡皂苷a和柴胡皂苷d的含量。结果：苦杏仁薄层鉴别方法具有专属性；柴胡皂苷a和柴胡皂苷d分别在0.068～1.70μg（r＝0.9999）和0.058～1.45μg（r＝0.9998）范围内线性关系良好，平均回收率分别为99.7％（RSD为0.75％）、96.5％（RSD为1.40％）。结论：所建立的方法合理可行，重复性好，可用于柴银口服液的质量控制。
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| 关 键 词： | 柴银口服液 薄层色谱 高效液相色谱法 柴胡皂苷a 柴胡皂苷d |
| 收稿时间： | 2014-06-03 |
| 修稿时间： | 2014-09-16 |
Quality standard for Chaiyin oral solution |
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| Shi Guosheng,Xie Qiangsheng,Li Qiyan and Wang Yutuan. Quality standard for Chaiyin oral solution[J]. , 2014, 15(5): 343-347 |
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| Authors: | Shi Guosheng Xie Qiangsheng Li Qiyan Wang Yutuan |
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| Affiliation: | (Shandong Institute for Food and Drug Control, Jinan 250101 ) |
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| Abstract: | Objective：To improve the methods of identification and assay of Chaiyin Mixture.Methods：Armeniacae Semen Amarum was identified by TLC and the contents of saikosaponin a and saikosaponin d were determined by HPLC.Results：The TLC spots of Armeniacae semen Amarum were fairly clear.The linear ranges of saikosaponin a and saikosaponin d were 0.068-1.70μg（ r=0.9999） and 0.058-1.45 μg（r=0.9998）, the average recoveries were 99.7%（RSD=0.75%） and 96.5%（RSD=1.40%） respectively.Conclusion：The results indicated that the methods were reasonable, feasible and highly reproducible, which could be used for the quality control of Chaiyin Mixture. |
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| Keywords: | Chaiyin Mixture TLC HPLC saikosaponin a saikosaponin d |
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