C-13 and H-1 NMR Assignments of the Chamigrenes Prepacifenol and Dehydroxyprepacifenol Epoxioes |
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| Authors: | Carlos R. Kaiser Liane F. Pitombo Angelo C. Pinto |
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| Affiliation: | Institute de Qulmica-DQO, Universidade Federal do Rio de Janeiro, Ilha do Fund?o , CT, Bloco A, 6° andar, 21949-900, Rio de Janeiro, RJ, BRASIL |
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| Abstract: | A complete assignment of the signals in the 1H and 13C NMR spectra and the stereostructural analysis of the compounds prepacifenol epoxide and the new dehydroxyprepacifenol epoxide are presented. These compounds were extracted from the marine mollusc Aplysia dactylomela and represent the first occurrence of chamigrenes found in Brazilian waters. The NMR analyses are supported by NOE difference and COSY experiments and also by gradient selected HMBC, HSQC-TOCSY and HSQC-DE. 1H spectra simulations were done for the final fitting of the chemical shifts and coupling constants. |
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| Keywords: | chamigrenes prepacifenol epoxide dehydroxyprepacifenol epoxide 1H and 13C NMR COSY NOE difference HMBC/GS HSQC-TOCSY/GS HSQC-DE/GS |
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