| 板蓝根化学成分研究 |
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| 引用本文： | 徐晗,方建国,王少兵,刘焱文.板蓝根化学成分研究[J].中国药学杂志,2003,38(6):418-419. |
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| 作者姓名： | 徐晗 方建国 王少兵 刘焱文 |
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| 作者单位： | 1. 华中科技大学同济医学院,湖北,武汉,430030
2. 湖北中医学院,湖北,武汉,430061 |
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| 基金项目： | 国家自然科学基金资助项目 ( 3980 0 193) |
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| 摘 要： | 目的从板蓝根中提取分离活性成分。方法板蓝根用95%乙醇渗漉，不同极性溶剂提取，再用硅胶柱色谱分离单体，测定化合物的理化常数和波谱数据，鉴定其化学结构。结果分离得到5个化合物，分别鉴定为：β-谷甾醇(β-sitosterol Ⅰ)，棕榈酸(plamitic acid Ⅱ)，琥珀酸(succinic acid Ⅲ)，胡萝卜苷(daucosterol Ⅳ)和远志醇(polygalitol Ⅴ)。结论化合物Ⅲ，Ⅴ为首次从该植物中分离得到。
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| 关 键 词： | 板蓝根 化学成分 提取分离 结构鉴定 |
| 文章编号： | 1001-2494(2003)06-0418-02 |
| 收稿时间： | 2002-11-11; |
| 修稿时间： | 2002年11月11 |
Studies on the chemical constituents of Isatis indigotica in root |
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| XU Han ,FANG Jian guo ,WANG Shao bing ,LIU Yan wen.Studies on the chemical constituents of Isatis indigotica in root[J].Chinese Pharmaceutical Journal,2003,38(6):418-419. |
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| Authors: | XU Han FANG Jian guo WANG Shao bing LIU Yan wen |
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| Affiliation: | XU Han 1,FANG Jian guo 1*,WANG Shao bing 2,LIU Yan wen 2 |
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| Abstract: | OBJECTIVE The bio-active constituents were expected to be obtained from the root of Isatis indigotica Fort.METHOD S The powdered plant material was percolated with 95% alcohol.The percolate was extracted with different solvents.The extract was analyzed via chromatography on silica gel column.The compounds were identified by their physicochemical properties and spectral data (MS,1H-NMR,13C-NMR and IR) respectively.RESULTS Five compounds were isolated from the root of Isatis Indigotica Fort.They were β-sitosterol (Ⅰ)，plamitic acid (Ⅱ)，succinic acid (Ⅲ)，daucosterol (Ⅳ) and polygalitol(V).CONCLUSION Compound Ⅲ and Ⅴ were isolated from this plant for the first time. |
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| Keywords: | Isatis indigotica Fort chemical constituent isolation identification |
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