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健脾散结丸治疗恶性肿瘤化疗后脾虚证临床观察
引用本文:王红岩,李冬云,陈赐慧,李园,黄金昶,谭煌英,朱世杰,程志强,万冬桂,李学,李利亚,娄彦妮,崔慧娟. 健脾散结丸治疗恶性肿瘤化疗后脾虚证临床观察[J]. 中日友好医院学报, 2011, 0(5): 267-269. DOI: 10.3969/j.issn.1001-0025.2011.05.003
作者姓名:王红岩  李冬云  陈赐慧  李园  黄金昶  谭煌英  朱世杰  程志强  万冬桂  李学  李利亚  娄彦妮  崔慧娟
作者单位:1. 北京中医药大学第一临床医学院,北京100700;中日友好医院中西医结合肿瘤内科,北京 100029
2. 北京中医药大学第一临床医学院血液肿瘤科,北京,100700
3. 北京中医药大学研究生院,北京,100029
4. 中日友好医院中西医结合肿瘤内科,北京,100029
摘    要:目的:观察健脾散结丸治疗恶性肿瘤化疗后脾虚证患者的疗效及用药安全性。方法:60例恶性肿瘤化疗后出现脾虚证的患者,随机分为对照组和试验组,各30例。试验组化疗结束后开始口服健脾散结丸(浓缩丸),10g/次,Bid,共2周;对照组口服健脾益肾颗粒,10g/次,Bid,共2周。2周后评价疗效,记录2组患者在服药前后的脾虚证候评分、舌苔、脉象的变化及评分、卡氏评分及体重变化的评分;服药前后测定患者的血、尿、便常规,肝肾功能,心电图。结果:服药前2组患者具有可比性;服药后,试验组患者在倦怠乏力、食少纳呆、恶心呕吐及腹胀便秘4个证候的改善优于对照组;且2组患者疗效存在显著性差异(P〈0.01)。血、尿、便常规及肝肾功能、心电图的检查证明该药无明显毒副反应。结论:健脾散结丸可改善恶性肿瘤化疗后脾虚证候患者的临床症状,提高患者生存质量,用于临床较为安全。

关 键 词:健脾散结丸  恶性肿瘤  化疗  脾虚证

Clinical study of Jianpisanjie pills treating spleen deficiencies after chemotherapy
WANG Hong-yan,LI Dong-yun,CHEN Xi-hui,et al. Clinical study of Jianpisanjie pills treating spleen deficiencies after chemotherapy[J]. Journal of China-Japan Friendship Hospital, 2011, 0(5): 267-269. DOI: 10.3969/j.issn.1001-0025.2011.05.003
Authors:WANG Hong-yan  LI Dong-yun  CHEN Xi-hui  et al
Affiliation:WANG Hong-yan,LI Dong-yun,CHEN Xi-hui,et al Department of Hematology&Oncology,the First Clinical Hospital of Beijing Chinese Medical University,Beijing 100700,China
Abstract:Objective:To observe the efficacy and safety of the Chinese medicine pills(Jianpisanjie pills)for the patients who had spleen deficiencies after the chemotherapy of malignant carcinoma.Methods:Sixty patients who were consistent with the standards of the choice with the syndromes of spleen deficiencies after chemotherapy were divided into two groups randomly.The patients of study group(n=30)took Jianpisanjie pills for 2 weeks while the patients of control group(n=30)took Jianpiyishen pills for 2 weeks.At the...
Keywords:Jianpisanjie pills  malignant carcinoma  chemotherapy  spleen deficiency  
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