| 紧密连接蛋白Claudins与胃肠道肿瘤 |
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| 引用本文： | 蒋锐,裴海平.紧密连接蛋白Claudins与胃肠道肿瘤[J].国际肿瘤学杂志,2009,36(8). |
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| 作者姓名： | 蒋锐 裴海平 |
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| 作者单位： | 中南大学湘雅医院胃肠外科,长沙,410008 |
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| 摘 要： | Claudins是一种表达于上皮细胞和内皮细胞的紧密连接蛋白,研究发现其异常表达与胃肠道肿瘤的发生及转移有关.Claudim对胃肠道肿瘤的诊断、治疗及预后评估有着广阔的应用前景.
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| 关 键 词： | 胃肠道肿瘤 连接蛋白类 |
Tight junction proteins-Claudins and gastrointestinal neoplasms |
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| Abstract: | Claudius is a kind of tight junction (TJ) proteins expressed on epithelial and endothelial cells,abnormal expression of claudins has been documented in the occurrence and metastasis of gastrointestinal neoplasms. Investigating the expression of clandins in turnout cell has great significance for the diagnosis, thera-py and prognosis of gastrointestinal neoplasms. |
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| Keywords: | Gastrointestinal neoplasms Connexins |
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