| H IV 感染合并恶性肿瘤患者临床资料分析 |
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| 引用本文： | 何萌,李云霄,李宏,林昌海,王亚丽,吴立翔.H IV 感染合并恶性肿瘤患者临床资料分析[J].检验医学与临床,2014(17):2392-2393. |
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| 作者姓名： | 何萌 李云霄 李宏 林昌海 王亚丽 吴立翔 |
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| 作者单位： | 重庆市肿瘤研究所临床检验中心,重庆400030 |
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| 摘 要： | 目的：探讨人类免疫缺陷病毒（HIV）感染患者继发恶性肿瘤的危险因素。方法对2003年1月至2013年8月确诊的HIV感染患者临床资料进行回顾性分析。结果HIV感染合并恶性肿瘤患者以50岁以上的人群为主，恶性肿瘤类型以非霍杰金淋巴瘤（NHL）为主，占25．33％；其次是宫颈癌，占18．67％。HIV感染合并恶性肿瘤患者CD4＋T淋巴细胞计数、CD4＋/CD8＋比值和自然杀伤细胞计数明显低于单纯HIV感染患者（P＜0．05）。结论年龄和免疫功能缺陷均增加了HIV感染者继发恶性肿瘤的风险。
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| 关 键 词： | 人类免疫缺陷病毒 恶性肿瘤 获得性免疫缺陷综合征 |
Analysis of clinical data of patients combined with HIV infection and malignant tumor |
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| HE Meng,LI Yun-xiao,LI Hong,LIN Chang-hai,WANG Ya-li,WU Li-xiang.Analysis of clinical data of patients combined with HIV infection and malignant tumor[J].Laboratory Medicine and Clinic,2014(17):2392-2393. |
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| Authors: | HE Meng LI Yun-xiao LI Hong LIN Chang-hai WANG Ya-li WU Li-xiang |
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| Affiliation: | (Centre of Clinical Laboratory, Cancer Research Institute of Chongqing , Chongqing 400030, China) |
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| Abstract: | Objective To investigate the risk factors of human immunodeficiency virus （HIV） infection-related malignant tumor .Methods The clinical data of patients with HIV infection ,diagnosed during January 2003 and Au-gust 2013 ,were collected and analyzed .Results Most of patients combined with HIV infection and malignant tumor were more than 50 years old .The most common types of malignant tumor were non-Hodgkin′s lymphoma （NHL） , accounting for 25 .33% ,and cervical cancer ,accounting for 18 .67% .The CD4＋ cell counts ,CD4＋ /CD8＋ ratio and natural killer cell counts in patients combined with HIV infection and caner were lower than patients only with HIV infection （P〈0 .05） .Conclusion Age and immunodeficiency could increase the risk of HIV infection-related malig-nant tumor . |
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| Keywords: | immunodeficiency virus malignant tumor acquired immune deficiency syndrome |
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