纳米抗菌剂抑菌杀菌性能研究

目的：检测纳米抗菌剂对标准菌株的杀菌、抑菌性能和高温对其抑菌效果的影响。方法：目标菌为大肠杆菌、金黄色葡萄球菌和白色念珠菌，通过悬液定量杀灭试验和抑菌环试验检测纳米抗菌剂的杀菌、抑菌能力。结果：水溶性纳米抗菌膜溶于5ml灭菌水中作用l0min可杀灭95．39％的金黄色葡萄球菌和93．28％的白色念珠菌，复合了纳米银的抗菌医用棉条、烧烫伤贴、创伤贴对大肠杆菌和金黄色葡萄球菌的抑菌环直径大于l0mm，对白色念珠菌的抑菌环直径大于7mm。结论：纳米抗菌剂对细菌繁殖体和白色念珠菌具有良好的抑菌、杀菌作用，高压灭菌处理对纳米银抗菌剂抑菌效果影响不大，但织物构造对其抑菌效果有影响。

The Germicidal and Inhibitory Efficacy of Nano-Antimicrobial

Objective To know the germicidal and inhibitory efficacy of nano-antimicrobial to criterion bacteria. To investigate the influence under high temperature. Methods Taking Escherichia coli, Staphylococcus aureus and Candida albicans as target bacteria ,suspension quantitative bactericidal test and inhibitory test were carried out. Result The killing rates to Staphylococcus aureus and Candida albicans exposed to 1:5 (w/v)solution for 10 min was 95.39% and 93.28% respectively. The diameter of inhibition ring was more than 10 mm on Escherichia coli and Staphylococcus aureus. On Candida albicans ,the diameter of inhibition ring was more than 7 mm. Conclusion The germicidal and inhibitory efficacy of nano-antimicrobial was fine to bacterium and Candida albicans. The inhibitory efficacy did not change obviously after disinfection of autoclave. The density and thickness of the materials could influence the bacteriostatic efficacy.