PDMS microfluidics developed for polymer based photonic biosensors |
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Authors: | P Fürjes E G Holczer E Tóth K Iván Z Fekete D Bernier F Dortu D Giannone |
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Affiliation: | 1.Institute for Technical Physics and Materials Science,Research Centre for Natural Sciences,Budapest,Hungary;2.Faculty of Information Technology and Bionics,Pázmány Péter Catholic University,Budapest,Hungary;3.Multitel asbl,Mons,Belgium |
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Abstract: | In this work, advances in the fabrication technology and functional analysis of a polymer microfluidic system—as a significant part of a developed polymer photonic biosensor—are reported. Robust and cost-effective microfluidics in PDMS including sample preparation functions is designed and realized by using SU-8 moulding replica. Surface modification strategies using Triton X-100 and PDMS-PEO and their effect on device sealing and non-specific protein adsorption are investigated by contact angle measurement and in situ fluorescence microscopy. |
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