| 大叶钩藤总生物碱提取溶剂的研究及钩藤碱的纯度测定 |
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| 引用本文： | 李维锋,姜建国,王定勇,陈健,李艳敏.大叶钩藤总生物碱提取溶剂的研究及钩藤碱的纯度测定[J].食品科技,2007,32(8):156-158. |
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| 作者姓名： | 李维锋 姜建国 王定勇 陈健 李艳敏 |
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| 作者单位： | 1. 华南理工大学轻工与食品学院,广州,510640
2. 广州药学院药科学院,广州,510006 |
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| 摘 要： | 目的:筛选大叶钩藤总生物碱工业化提取的适宜溶剂,分离纯化得到钩藤碱并测定其纯度。方法:用不同的溶剂提取大叶钩藤的总生物碱,柱层析分离得到钩藤碱晶体,用HPLC测定晶体的纯度。结论:溶剂的选择直接影响总生物碱的提取量,氯仿是大叶钩藤总生物碱工业化提取的适宜溶剂,用通过柱层析可以得到纯度高达为95.49%的钩藤碱晶体。
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| 关 键 词： | 大叶钩藤 总生物碱 提取溶剂 钩藤碱 |
| 文章编号： | 1005-9989(2007)08-0156-03 |
| 修稿时间： | 2007年1月19日 |
Study on the solvents extracting the total alkaloids from Uncaria macrophylla Wall and the purity of Rhynchophylline |
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| LI Wei-feng,JIANG Jian-guo,Wang DING-yong,CHEN Jian,LI Yan-min.Study on the solvents extracting the total alkaloids from Uncaria macrophylla Wall and the purity of Rhynchophylline[J].Food Science and Technology,2007,32(8):156-158. |
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| Authors: | LI Wei-feng JIANG Jian-guo Wang DING-yong CHEN Jian LI Yan-min |
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| Abstract: | Objective: To optimize the optimum solvent extracting the total alkaloids from Uncaria macrophylla Wall in industrial production and determine the purity of Rhynchophylline isolated from the total alkaloids. Me-thods: The total alkaloids in Uncaria macrophylla Wall were extracted by using different solvents. Rhynchophylline was separated from the total alkaloids by dry column chromatography and was determined the purity by HPLC. Results: The amounts of the total alkaloids extracted by different solvents were also distinctively different. The chloroform was the optimum solvent. The purity of Rhynchophylline separated from the total alkaloids was 95.49%. |
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| Keywords: | Uncaria macrophylla Wall total alkaloids extracting solvent Rhynchophylline |
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