中孕B超产前检查联合母血清标记物对21-三体综合征的临床诊断价值

目的:探讨中孕B超产前检查出现阳性征,及联合母体血清标记物指标:甲胎蛋白(AFP)、游离雌三醇(uE3)、血清总β绒毛膜促性腺激素(hCG)的含量检查对21-三体综合征的产前筛查和诊断的可行性、有效性和必要性.方法:回顾了中孕B超产前检查联合母血清标记物对21-三体综合征检出率.结果:中孕B超产前检查的阳性征,联合母体...

The Dianosis Value of Prenatal Ultrasound Screening Combined with Prenatal Maternal Serum Markers Detecting in Trimester Pregnancy for the 21-trisomy Syndrome

Objective：To explore the feasibility,effectiveness and necessity of the prenatal ultrasound screenings,combined with the content inspection of the mothers’ prenatal maternal serum markers：in trimester pregnancy Alpha-fetoprotein（AFP）,free estriol（uE3）,total serum β human chorionic gonadotropin（hCG）in the 21-trisomy syndrome.Method：We summarized the detection rate of the 21-trisomy syndrome by prenatal ultrasound screening and the prenatal maternal serum markers.Result：The detection rate in terms of the positive signs of the prenatal ultrasound screening in trimester pregnancy combined with the prenatal maternal serum markers in the 21-trisomy syndrome diagnosis was 80%-90%.Conclusion：The prenatal ultrasound screening in trimester pregnancy combined with prenatal maternal serum markers in the 21-trisomy syndrome diagnosis is a non-invasive checking method,not only can reduce the abnormal or deformed children are born,can also reduce the invasive inspection;It has the davantage of clinically simple,application and testing of a wide range of safe and effective,cost-effective,with higher screening detection rate,and reduce the intrusion caused by the check normal fetal abortion rate.