| 左炔诺孕酮宫内缓释系统治疗子宫腺肌病的临床观察 |
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| 引用本文： | 钱晓萍,周秋萍,刘妮平.左炔诺孕酮宫内缓释系统治疗子宫腺肌病的临床观察[J].中国妇幼保健,2009,24(23):3220-3222. |
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| 作者姓名： | 钱晓萍 周秋萍 刘妮平 |
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| 作者单位： | 1. 南京医科大学附属常州第二医院妇科,江苏,常州,213003
2. 广西壮族自治区人民医院妇产科 |
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| 摘 要： | 目的:观察左炔诺孕酮宫内缓释系统(LNG-IUS)治疗子宫腺肌病的临床疗效。方法:52例子宫腺肌病患者于月经期的第5~7天放置LNG-IUS,观察术前、术后1个月、3个月、6个月及1年后痛经程度、月经量及子宫大小的变化。结果:放置LNG-IUS后3个月,月经量显著减少,降低为治疗前的(28±5)%,治疗前后比较差异有统计学意义(P<0.01);28例贫血患者血红蛋白含量显著增加,由治疗前的(85±24)g/L恢复至(118±7)g/L;子宫大小均较前缩小,由治疗前的(17.8±1.8)cm减小为(17.5±1.6)cm,但差异无统计学意义(P>0.01);放置LNG-IUS后12个月,52例患者中49例患者痛经完全消失,3例患者痛经评级降低≥2个级别,但疼痛未完全消失。结论:LNG-IUS治疗子宫腺肌病近期疗效显著。
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| 关 键 词： | 左炔诺孕酮 药物释放系统 子宫腺肌病 痛经 |
Clinical observation on the effect of levonorgestrel-releasing intrauterine system on adenomyosis |
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| QIAN Xiao-Ping,ZHOU Qiu-Ping,LIU Ni-Ping.Clinical observation on the effect of levonorgestrel-releasing intrauterine system on adenomyosis[J].Maternal and Child Health Care of China,2009,24(23):3220-3222. |
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| Authors: | QIAN Xiao-Ping ZHOU Qiu-Ping LIU Ni-Ping |
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| Abstract: | Objective:To observe the clinical efficacy of levonorgestrel-releasing intrauterine system(LNG-IUS) in the treatment of adenomyosis.Methods:52 patients with adenomyosis were inserted of LNG-IUS on the fifth～seventh days in menstrual cycle.The changes of dysmenorrhea,menstrual blood volume and uterine volume were compared after 1,3,6 and 12 months.Results:After 3 months,the menstrual blood volume reduced to(28±5)% of that before treatment(P<0.01).Hemoglobin level recovered from(85±24)g/L to(118±7)g/L in 28 patients with anemia.The size of uteri reduced from(17.8±1.8)cm to(17.5±1.6)cm(P>0.01).After 12 months,49 patients with dysmenorrhea completely relieved and 3 patients significantly alleviated(≥2 grade).Conclusion:LNG-IUS is an effective and safe method in the short-term treatment of adenomyosis. |
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| Keywords: | Levonorgestrel Drug releasing systems Adenomyosis Dysmenorrhea |
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