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病灶刮除植骨术治疗中青年膝关节周围骨巨细胞瘤的疗效分析
引用本文:聂治军,袁启令,董向辉,常彦海,王金堂.病灶刮除植骨术治疗中青年膝关节周围骨巨细胞瘤的疗效分析[J].现代肿瘤医学,2018,0(24):4001-4003.
作者姓名:聂治军  袁启令  董向辉  常彦海  王金堂
作者单位:1.陕西省人民医院骨科,陕西 西安 710068;2.西安交通大学医学院第一附属医院骨科,陕西 西安 710061
基金项目:陕西省国际科技合作与交流计划项目(编号:2017KW-051)
摘    要:目的:探讨中青年患者膝关节周围骨巨细胞瘤(giant cell tumor,GCT)的临床特征、影像学特点及手术治疗效果。方法:回顾性分析2014年5月至2016年1月在陕西省人民医院就诊并经组织病理学确诊的GCT患者共32例。其中男14例,女18例,均为初次手术治疗患者。所有患者均行膝关节周围GCT病灶刮除植骨术。结果:患者均获得随访,时间24~30个月,术后4例复发,复发率12.5%,末次随访时根据MSTS标准评定疗效:优21例,良8例,可3例,差0,总体优良率90.6%。结论:膝关节周围GCT患者行病灶刮除植骨术疗效满意,正确使用广泛刮除术配合辅助方法是降低其复发率的重要手段。

关 键 词:膝关节  骨巨细胞瘤  手术治疗  临床特点  复发

Efficacy analysis of intracapsular curettage and bone grafting in the treatment of giant cell tumor around the knee joint in young and middle-aged patients
Nie Zhijun,Yuan Qiling,Dong Xianghui,Chang Yanhai,Wang Jintang.Efficacy analysis of intracapsular curettage and bone grafting in the treatment of giant cell tumor around the knee joint in young and middle-aged patients[J].Journal of Modern Oncology,2018,0(24):4001-4003.
Authors:Nie Zhijun  Yuan Qiling  Dong Xianghui  Chang Yanhai  Wang Jintang
Affiliation:1.Department of Orthopaedics,Shaanxi Provincial People's Hospital,Shaanxi Xi'an 710068,China;2.Department of Orthopaedics,the First Affiliated Hospital of Medical School of Xi'an Jiaotong University,Shaanxi Xi'an 710061,China.
Abstract:Objective:To explore the clinical characteristics,imaging features and clinical effect of the giant cell tumor(GCT) around the knee joint in young and middle-aged patients.Methods:Retrospectively analyse a total of 32 cases with giant cell tumor of bone,which were diagnosed by histopathology from SPPH,from May 2014 to Jan 2016,including 14 cases of male,18 cases of female.All patients were treated with primary surgery.All patients underwent curettage and bone grafting for giant cell tumor around the knee joint.Results:All patients were followed up for 24~30 months.There were 4 cases of recurrence,and the recurrence rate was 12.5%.The postoperative functional evaluation at the last follow-up was made according to MSTS standard:Excellent in 21 cases,good in 8 cases,fair in 3 cases and poor in 0.Excellent and good rate was 90.6%.Conclusion:Intracapsular curettage and bone grafting for giant cell tumor around the knee joint is a good option and has a satisfactory effect.It is an important method to reduce the recurrence rate with using extensive curettage and adjuvant method.
Keywords:knee joint  giant cell tumor of bone  surgical treatment  clinical characteristics  recurrence
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