60例新生儿惊厥临床分析

目的探讨早期新生儿惊厥的病因与治疗,有效控制惊厥的发作,以减少新生儿惊厥及后遗症的发生。方法临床分析我院5年来收治的60例新生儿惊厥的临床特点、实验室检查结果、治疗及转归情况。结果痊愈出院46例,好转后出院7例,放弃治疗4例,死亡3例。临床以缺氧缺血性脑病(HIE)和颅内出血(ICH)多见,发病时间多在生后3 d内,其次为低血糖和低钙血症,发病时间多在生后1周,而后天性感染发生新生儿惊厥的时间相对较晚。结论早期发生惊厥者主要与HIE、ICH有关,其次是低血糖和低钙血症。苯巴比妥仍是首选的抗惊厥药物。

Clinical Analysis of 60 Cases of Neonatal Convulsions

Objective To investigate the etiology and treatment of early neonatal seizures,and effective control of convulsion seizures,in order to reduce the occurrence of sequelae of neonatal seizures. Methods clinical analysis of our hospital 5 years 60 cases of neonatal convulsions of the clinical features,laboratory findings,treatment and prognosis. Results 46 cases were cured,7 cases improved after discharge,abandoned in the treatment of 4 cases,3 cases of death.Clinical to hypoxic ischemic encephalopathy(HIE) and intracranial hemorrhage(ICH) see more,time of onset in 3 d after birth,followed by hypoglycemia and hypocalcemia,time of onset in 1 week after birth,and then acquired infection of neonatal seizures relatively late. Conclusion early seizures occurring mainly with HIE,ICH,followed by hypoglycemia and hypocalcemia,phenobarbital is still the preferred anticonvulsant drugs.