广西地区京族人群高尿酸血症及影响因素分析

目的：调查广西东兴市18~84岁京族人群高尿酸血症患病率并对其相关因素进行分析。方法：对757名健康查体人群进行横断面调查,应用Logistic回归分析影响因素与高尿酸血症的相关性。结果：血尿酸平均（306.39±93.98）μmol/L,男性平均为（353.88±95.20）μmol/L,女性均为（273.63±77.84）μmol/L,两者差异有统计学意义（P〈0.001）。男性高尿酸血症患病人数71名,患病率为23%;女性53名,患病率为11.8%,差异有统计学意义（P〈0.001）,总体上,高尿酸血症患病率随年龄增长呈升高趋势（P〈0.001）。18~44岁年龄组：高尿酸血症患病率男性为19.9%、女性为6%,差异有统计学意义（P〈0.001）。Logistic回归分析显示：性别、年龄、体重指数（BMI）、高血脂与高尿酸血症发病独立相关（P〈0.05）。结论：广西东兴市京族人群高尿酸血症患病率较高,男性多于女性;性别、年龄、BMI、高血脂可能为高尿酸血症的危险因素。

ANALYSIS ON THE PREVALENCE OF HYPERURICEMIA AND ITS RISK FACTORS IN THE JING POPULATION OF GUANGXI REGION

Objective. To investigate the prevalence of hyperuricemia and its risk factors in the Jing population of Guangxi region. Methods： A total of 757 residents aged from 18 to 84 years from Dongxing city was surveyed by a cross-sectional study. Physical examination was carried out and biochemical test was performed. The prevalence of hyperuricemia and its risk factors were analyzed by Logistic regression analysis. Results： The average levels of blood uric acid were significantly higher in males （353.88±95.20 /,mol/L） than in females （273.63± 77.84 /,mol/L, P % 0. 001）. The prevalence of hyperuricemia was 23% in males and 11.80/oo in females （ P〈0. 001）. For the whole population, the increase of the hyperuricemia prevalence was increased with the age （ P 〈0. 001）. When the subjects were divided into 3 groups according to age, we found that the prevalence of hyperuricemia was significantly higher in males （19.9%） than in females （6%, P 〈0. 001） in group aged from 18 to 44 years. Logistic regression analysis showed that gender, age, body mass index and high cholesterol were independently associated with the prevalence of hyperuricemia （ P〈0.05）. Conclusion. The prevalence of hyperuricemia is rather high in the Jing population of Dongxing city, it is higher in males than in females. Gender, age, body mass index and high cholesterol may be risk factors for hyperuricemia.