| 枝管藻多糖的提取及其抗凝血活性的初步研究 |
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| 引用本文： | 王静凤,张学成,姜国良,葛源,吴志强,陈先锋. 枝管藻多糖的提取及其抗凝血活性的初步研究[J]. 中国海洋大学学报(自然科学版), 2003, 33(1): 75-79 |
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| 作者姓名： | 王静凤 张学成 姜国良 葛源 吴志强 陈先锋 |
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| 作者单位： | 中国海洋大学海洋生命学院,青岛,266003 |
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| 基金项目： | 863计划项目 ( 2 0 0 1AA62 50 30 )资助 |
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| 摘 要： | 探讨枝管藻多糖的提取方法 ,并对枝管藻多糖的抗凝血活性进行研究。采用酶解 -热水浸提法提取的枝管藻多糖能够显著延长小鼠全血凝血时间、大鼠体外凝血酶原时间和白陶土部分凝血活酶时间 ,且呈明显的量 -效关系。提示枝管藻多糖具有较强的抗凝血作用。
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| 关 键 词： | 枝管藻多糖 抗凝血 凝血酶原时间 白陶土部分凝血活酶时间 |
| 文章编号： | 1001-1862(2003)01-075-05 |
| 修稿时间： | 2002-08-02 |
Preliminary Studies on the Extraction Of Polysaccharide From Cladosiphon okamuranusa and Its Anti-Coagulation Activity |
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| Wang Jingfeng Zhang Xuecheng Jiang GuoliangGe Yuan Wu Zhiqiang Chen Xianfeng. Preliminary Studies on the Extraction Of Polysaccharide From Cladosiphon okamuranusa and Its Anti-Coagulation Activity[J]. Periodical of Ocean University of China, 2003, 33(1): 75-79 |
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| Authors: | Wang Jingfeng Zhang Xuecheng Jiang GuoliangGe Yuan Wu Zhiqiang Chen Xianfeng |
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| Abstract: | The method of extraction of polysaccharide from Cladosiphon okamuranusa (CP) and its anti-coagulation activity were studied. By using enzyme-hot water method the polysaccharides isolated could markedly elongate the blood coagulation time in mice, the prothrombin time and KPTT in rats. It is suggested that CP has significant anti-coagulation activity. |
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| Keywords: | polysaccharide from Cladosiphon okamuranusa (CP) anti-coagulation prothrombin time KPTT |
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