腹腔镜与开腹子宫肌瘤剔除术近期临床疗效及组织损伤程度观察

目的：比较腹腔镜下与开腹子宫肌瘤剔除术近期临床疗效和组织损伤程度。方法：选取符合标准的患者80例,随机分为观察组和对照组各40例。观察组应用腹腔镜下子宫肌瘤剔除术,对照组应用开腹子宫肌瘤剔除术,比较二者临床疗效和血清超敏C反应蛋白（hs-CRP）水平。结果：观察组患者手术持续时间稍长于对照组,但是差异无统计学意义（P〉0.05）;观察组术中出血量、术后镇痛、术后病率、下床活动时间、术后肛门排气时间及住院时间均优于对照组,差异有统计学意义（P〈0.05）。两组手术前血清hs-CRP水平相似,差异无统计学意义（P〉0.05）;两组术后第1天血清hs-CRP水平较术前均升高（P〈0.05）,但是观察组升高幅度较对照组小（P〈0.05）;术后第3天两组血清hsCRP水平开始下降,术后第5天,对照组组血清hs-CRP水平高于观察组,差异有统计学意义（P〈0.05）。结论：腹腔镜下子宫肌瘤剔除术组织创伤小,术后恢复快,有利于妇女的身体健康。

Observation on the Short-term Clinical Effects and Tissue Damage Degrees of Laparoscopic and Open Myomectomies

Objective： To compare the short-term clinical therapeutic effects and tissue damage degrees between laparoscopic myomectomy and open myomectomy. Method： 80 eligible patients were selected and randomly divided into observation group and control group,40 patients in each group. The observation group used laparoscopic myomectomy,while the control group used open myomectomy,and the clinical therapeutic effects and serum high sensitive C reaction protein（ hs-CRP） levels in the patients of the two groups were compared.Result： The operative time of the patients in the observation group was slightly longer than that of the control group,but the difference was statistically insignificant（ P 〉0.05）; The intra-operative bleeding volume,postoperative analgesia,postoperative complication incidence,out-of-bed activity time,postoperative time of passage of gas by anus and length of stay in hospital of the patients in the observation group were all better than those of the control group,and the differences were statistically significant（ P〈0.05）. The pre-operative serum hs-CRP levels of the patients of the two groups were similar,and the difference was statistically insignificant（ P〉0.05）; in 1 day after the surgeries,the serum hs-CRP levels of the patients of the two groups were both increased when compared with those before the surgeries（ P〈0.05）,but the increasing extent of the observation group was smaller than that of the control group（ P〈0.05）; in 3 days after the surgeries,the serum hs-CRP levels of the patients of the two groups started to decrease; in 5 days after the surgeries,the serum hs-CRP level of the patients in the control group was higher than that of the observation group,and the difference was statistically significant（ P〈0.05）.Conclusion： Laparoscopic myomectomy has advantages of small tissue damage and rapid postoperative recovery,and it is benefit to women＇s physical health.