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血必净注射液治疗脓毒症的疗效分析
引用本文:刘鸿翔,南勇,诸俊欢,陈飞,吴海英,石斌.血必净注射液治疗脓毒症的疗效分析[J].临床急诊杂志,2013(2):56-58.
作者姓名:刘鸿翔  南勇  诸俊欢  陈飞  吴海英  石斌
作者单位:上海市松江区中心医院(上海交通大学附属第一人民医院松江分院)急诊危重病科
摘    要:目的:评价血必净注射液对脓毒症的治疗效果。方法:将45例脓毒症患者随机分成2组,对照组(n=22)给予常规治疗;治疗组(n=23)在常规治疗基础上联合应用血必净100ml,静脉滴注1次/d,连用1周。治疗前后对患者进行APCACHEⅡ评分,白细胞计数、中性粒细胞比率及C反应蛋白定量,记录28d死亡率。结果:与对照组比较,治疗组的APCACHEⅡ评分,白细胞计数及C反应蛋白水平明显降低,28d死亡率也明显下降(P〈0.01)。结论:血必净注射液可阻断全身炎症反应综合症(SIRS)的病理反应过程,改善脓毒症患者的预后。

关 键 词:血必净注射液  脓毒症

Efficacy analysis of Xuebijing injection in the treatment of sepsis
LIU Hongxiang,NAN Yong,ZHU Junhuan,CHEN Fei,WU Haiying,SHI Bin.Efficacy analysis of Xuebijing injection in the treatment of sepsis[J].Journal of Clinical Emergency Call,2013(2):56-58.
Authors:LIU Hongxiang  NAN Yong  ZHU Junhuan  CHEN Fei  WU Haiying  SHI Bin
Affiliation:(Emergency Critical Care Division,Central Hospital of Songjiang District of Shanghai,Shanghai 201600,China)
Abstract:Objective:To evaluate the effect of Xuebijing injection on the treatment of sepsis. Method:45 septic patients were randomly divided into control group (n=22) and treatment group (n=23). The same as the control group receiving conventional treatment,the Xuebijing injection was used in the treatment group,a 100 ml per day for a week. The APCACHE Ⅱ score, white blood cell count, neutrophil ratio, C-reactive protein levels and 28 day mortality were recorded after treatment. Result:Compared with the control group,the APCACHE Ⅱ score,white blood cell count, C reactive protein levels and mortality at 28 clays were significantly decreased in the treatment group(P〈0.01). Conclusion: Xuebijing injection can block the pathological reactions of the systemic inflammatory response syndrome, and improve the prognosis of patients with sepsis.
Keywords:xuebijing injection  sepsis
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