165例胰头癌的外科治疗与预后分析

目的 探讨胰头癌的外科治疗方法对生存率的影响,分析影响预后的相关因素.方法 收集2004年1月至2009年12月165例胰头癌病例,将其分为根治性切除术(A组,n=33),姑息性切除术(B组,n=19),单纯胆肠吻合术(C组,n=95),胆肠吻合附加胃空肠吻合术(D组,n=11)和非手术(E组,n=7),观察各组生存时...

Surgical treatment and analysis of prognosis for 165 cases of carcinoma of head of pancreas

Objective To investigate the surgical treatment and analysis of prognosis for carcinoma of head of pancreas. Methods The 165 patients with carcinoma of head of pancreas admitted into our hospital from Jan. 2004 to Dec. 2009 were divided into 5 groups： radical resection group（A, n = 33）, palliative resection group （B, n = 19）, cholangio-jejunostomy group（C, n = 95）, gastrojejunostomy group （D, n = 11） and non-operation group（E, n = 7）. The survival rate and the risk factors were analyzed comparatively. Results The 1-, and 3-year survival rate was higher and mean survival time （14. 5 months） was longer in group A than in other groups （P〈0. 05）. The 1-year survival .rate in group B was higher than in group E （P〈0. 05）. The operation methods, tumor stages, margin-negative residual resection, lymph node metastasis, invasion of vessels and transfusion might influence the prognosis of patients. Conclusion The radical resection can improve the survival rate. Margin-negative residual resection and lymph node metastasis are independent prognostic factors.